• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Regorafenib Anhydrous

Regorafenib Anhydrous

Product ID R1627
Cas No. 755037-03-7
Purity ≥99%
Product Unit SizeCostQuantityStock
1 mg $47.80 In stock
5 mg $61.40 In stock
25 mg $102.30 In stock
100 mg $258.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Regorafenib is an orally bioavailable multikinase inhibitor. This compound is clinically used in the treatment of metastatic colorectal cancer and non-responsive gastrointestinal stromal tumors. Regorafenib displays anticancer chemotherapeutic and anti-angiogenic properties, selective primarily for VEGFR2 but also displaying inhibitory activity against TIE2, VEGFR1/3, PDGFR-β, FGFR1, c-Kit, RET, and B-Raf.

Product Info

Cas No.

755037-03-7

Purity

≥99%

Formula

C21H15ClF4N4O3

Formula Wt.

482.82

Chemical Name

Regorafenib

IUPAC Name

4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide

Synonym

BAY73-4506

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

R1627 MSDS PDF

Info Sheet

R1627 Info Sheet PDF

References

Abou-Elkacem L, Arns S, Brix G, et al. Regorafenib inhibits growth, angiogenesis, and metastasis in a highly aggressive, orthotopic colon cancer model. Mol Cancer Ther. 2013 Jul;12(7):1322-31. PMID: 23619301.

Wilhelm SM, Dumas J, Adnane L, et al. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer. 2011 Jul 1;129(1):245-55. PMID: 21170960.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E7329

    Ethoxyquin

    Quinoline, food preservative; HSP90 inhibitor.<...

    ≥90%
  • S0929

    SCH-772984

    ERK1/2 inhibitor.

    ≥97%
  • L186858

    Levomefolic acid

    Folic acid derivative

    ≥98%
  • B560000

    RAD51 inhibitor, B02

    RAD51 inhibitor.

    ≥98%
  • T5608

    α-Tocotrienol

    Antioxidant, vitamin E derivative found in vege...

    ≥98%
  • C3477

    Citalopram Hydrobromide

    SERT inhibitor.

    ≥98%
  • C4559

    Clomiphene Citrate

    Used for in vitro fertilization; FIASMA, SERM.<...

    ≥98%
  • S1061

    Small Cardioactive Peptide B

    Peptide found in molluscs, cardiomodulator.

    ≥95%
  • C0048

    Cambinol

    SIRT inhibitor.

    ≥98%
  • M1564

    S-Methyl-L-cysteine

    Antioxidant found in Brassicaceae family plants...

    ≥99%
  • P2918

    Phenylethyl-4-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥98%
  • C4402

    Cladribine

    Nucleoside (deoxyadenosine) analog; DNA chain t...

    ≥98%
  • M578522

    Monascin

    Fungal pigment found in red yeast rice

    ≥98%
  • F3454

    Fingolimod Hydrochloride

    Sphingosine 1-phosphate antagonist.

    ≥99%
  • T7003

    Trazodone Hydrochloride

    5-HT1A partial agonist, 5-HT2, histamine, α1/2...

    ≥98%
  • A5219

    Anethole Trithione

    Oltipraz analog, salivary gland secretion enhan...

    ≥98%
  • E6231

    (−)-Epicatechin

    Flavanol originally found in Camilla (green tea...

    ≥93%
  • A5056

    Amorolfine Hydrochloride

    14α-demethylase inhibitor.

    ≥98.5%
  • F1654

    Fenoldopam Mesylate

    Benzazepine derivative; D1 partial agonist, pot...

    ≥98%
  • M1777

    R-(−)-α-Methylbenzyl Isothiocyanate

    ITC, used as chiral agent.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only