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SKLB 610

SKLB 610

Product ID S4244
Cas No. 1125780-41-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $97.70 In stock
5 mg $211.10 In stock
25 mg $641.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

SKLB610 is an inhibitor of VEGFR2 that also inhibits PDGFR and FGFR2. SKLB610 exhibits anticancer chemotherapeutic and anti-angiogenic activities. In animal models of colorectal cancer and non-small cell lung cancer (NSCLC), SKLB610 decreases capillary tube formation, microvessel density, and tumor proliferation.

Product Info

Cas No.

1125780-41-7

Purity

≥98%

Formula

C21H16F3N3O3

Formula Wt.

415.37

IUPAC Name

N-Methyl-4-(4-{[3-(trifluoromethyl)benzoyl]amino}phenoxy)-2-pyridinecarboxamide

Synonym

SKLB610, SKLB-610

Solubility

Soluble in DMSO, not in water

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S4244 MSDS PDF

Info Sheet

S4244 Info Sheet PDF

References

Luo X, Li S, Xie Y, et al. Pharmacokinetic studies of a novel multikinase inhibitor for treating cancer by HPLC-UV. J Chromatogr Sci. 2013 Jan;51(1):17-20. PMID: 22710664.

Cao ZX, Zheng RL, Lin HJ, et al. SKLB610: a novel potential inhibitor of vascular endothelial growth factor receptor tyrosine kinases inhibits angiogenesis and tumor growth in vivo. Cell Physiol Biochem. 2011;27(5):565-74. PMID: 21691074.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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