• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Suramin Hexasodium

Suramin Hexasodium

Product ID S8169
Cas No. 129-46-4
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $150.30 Please Inquire
50 mg $342.50 In stock
250 mg $919.40 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Suramin is an inhibitor of GPCRs; it prevents guanine nucleotide exchange. Suramin inhibits SIRT, telomerase, and P2Y receptors; it also acts as an agonist at Ryanodine (RyR) receptors. Suramin exhibits anticancer, neuromodulatory, neuroprotective, antiviral, anti-parasitic, and antimalarial activities. In glioma cells, suramin inhibits cell proliferation and spheroid growth. This compound inhibits proliferation of enterovirus EV71 by preventing viral attachment to host cells. Additionally, suramin inhibits falcipain-2 activity in Plasmodium.

Product Info

Cas No.

129-46-4

Purity

≥98%

Formula

C51H34N6O23S6Na6

Formula Wt.

1429.19

Chemical Name

8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino- (4-methyl-3,1-phenylene)-carbonylimino]]bis-1,3,5- naphthalenetrisulfonic acid hexasodium salt

IUPAC Name

hexasodium;8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6, 8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl] carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3, 5-trisulfonate

Synonym

Suramin Sodium, Bayer 205, Antrypol, Germanin, Moranyl, Naganol, Naphuride

Solubility

Soluble in water. Sparingly soluble in alcohol. Insoluble in benzene, ether or chloroform.

Appearance

White crystalline powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

S8169 MSDS PDF

Info Sheet

S8169 Info Sheet PDF

References

Wang Y, Qing J, Sun Y, et al. Suramin inhibits EV71 infection. Antiviral Res. 2014 Mar;103:1-6. PMID: 24374150.

Marques AF, Esser D, Rosenthal PJ, et al. Falcipain-2 inhibition by suramin and suramin analogues. Bioorg Med Chem. 2013 Jul 1;21(13):3667-73. PMID: 23680445.

Sakkiah S, Arooj M, Kumar MR, et al. Identification of inhibitor binding site in human sirtuin 2 using molecular docking and dynamics simulations. PLoS One. 2013;8(1):e51429. PMID: 23382805.

Erguven M, Akev N, Ozdemir A, et al. The inhibitory effect of suramin on telomerase activity and spheroid growth of C6 glioma cells. Med Sci Monit. 2008 Aug;14(8):BR165-73. PMID: 18667993.

Abbracchio MP, Burnstock G, Boeynaems JM, et al. International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev. 2006 Sep;58(3):281-341. PMID: 16968944.

Wolner I, Kassack MU, Ullmann H, et al. Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676. Br J Pharmacol. 2005 Oct;146(4):525-33. PMID: 16056233.

Beindl W, Mitterauer T, Hohenegger M, et al. Inhibition of receptor/G protein coupling by suramin analogues. Mol Pharmacol. 1996 Aug;50(2):415-23. PMID: 8700151.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D5610

    Docosahexaenoic Acid (all cis-4,7,10,13,16,19)

    Essential fatty acid found in fish oil, involve...

    ≥98%
  • A9603

    5-Aza-2′-deoxycytidine

    Nucleoside (deoxycytidine) analog; DNMT inhibit...

    ≥98%
  • B0150

    Bambuterol Hydrochloride

    β2-adrenergic agonist, BChE inhibitor.

    ≥98%
  • S1843

    L-Selectin

    Endogenous adhesion molecule, binds PKC, calmod...

    ≥95%
  • K0117

    Kaempferol

    Flavonol found in various plant sources.

    ≥98%
  • M185777

    4-(Methylsulfinyl) butylamine

    ≥99%
  • S8251

    Sulfluramid

    Perfluorinated insecticide.

    ≥95%
  • P3561

    Piperlongumine

    Found in Piper longum; TxA2 antagonist, ubiquit...

    ≥98%
  • S5868

    Sorafenib

    c-Raf, Ret, VEGFR2 inhibitor, potential STAT3/5...

    ≥98%
  • G1310

    GDC-0349

    mTOR inhibitor.

    ≥98%
  • T2970

    Thrombin Receptor Agonist Peptide

    Peptide; PAR1 agonist.

    ≥95%
  • B5875

    Bosutinib, structural isomer

    Bosutinib isomer; Src and Abl inhibitor.

    ≥98%
  • R0105

    Rabeprazole Sodium

    H+/K+ ATPase and Scpc phosphatase inhibitor.

    ≥98%
  • T0100

    10-Deacetyltaxol

    Taxane found in Taxus; microtubule depolymeriza...

    ≥98%
  • N1978

    Neurokinin B

    Neuromodulator, biomarker

    ≥95%
  • A0958

    Aconitine

    Toxin found in Aconitum; voltage-gated Na+ chan...

    ≥95%
  • P6264

    PPQ-102

    Pyramido-pyrrolo-quinoxalinedione; CFTR blocker...

    ≥98%
  • T3096

    Thymosin α-1

    Endogenous peptide fragment, immunostimulant; ...

    ≥95%
  • S0459

    SB-590885

    B-Raf inhibitor.

    ≥97%
  • P6859

    Proctolin

    Neuropeptide found in crustaceans and insects.<...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only