Description
Sutezolid is an analog of linezolid that may be effective treatment for tuberculosis. A study using a PK/PD model has shown that sutezolid is 17-fold more potent than its metabolite U-603 against tuberculosis.
Product Unit Size | Cost | Quantity | Stock |
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Sutezolid is an analog of linezolid that may be effective treatment for tuberculosis. A study using a PK/PD model has shown that sutezolid is 17-fold more potent than its metabolite U-603 against tuberculosis.
Cas No. | 168828-58-8 |
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Purity | ≥98% |
Formula | C16H20FN3O3S |
Formula Wt. | 353.41 |
Chemical Name | (S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide |
IUPAC Name | N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
Synonym | PNU-100480; U-100480; PF-02341272 |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Wallis R, Dawson R, Friedrich S, et al. Mycobacterial activity of sutezolid (PNU-100480) in sputum (EBA) and bloowd (WBA) of patients with pulmonary tuberculosis. PLoS One. 2014 Apr 14;9(4):e94462. PMID: 24732289.
Zhu T, Friedrich S, Diacon A, et al. Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid intracellular Mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis. Antimicrob Agents Chemother. 2014 Jun;58(6):3306-3311. PMID: 24687496.
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