Description
Tamsulosin is an α1-adrenergic receptor antagonist that is clinically used to treat benign prostatic hyperplasia (BPH). Tamsulosin inhibits peristaltic activity, increases bladder blood flow, and decreases bladder overactivity.
Tamsulosin Hydrochloride
Product ID T0251
Cas No. 106463-17-6
Purity ≥98%
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Product Info
| Cas No. | 106463-17-6 |
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| Purity | ≥98% |
| Formula | C20H28N2O5S • HCl |
| Formula Wt. | 444.98 |
| Chemical Name | 5-[(2R)-2-[[2-(2-Ethoxy-phenoxy)-ethyl]]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride |
| IUPAC Name | 5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2- methoxybenzenesulfonamide;hydrochloride |
| Synonym | Flomax, Harnal, Pradif |
| Melting Point | 228-230°C |
| Solubility | Slightly soluble in water to 10 mM. Weakly soluble in methanol. DMSO to 100 mM. |
| Appearance | White Powder |
Shipping and Storage
| Store Temp | 4°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Okutsu H, Matsumoto S, Ohtake A, et al. Effect of tamsulosin on bladder blood flow and bladder function in a rat model of bladder over distention/emptying induced bladder overactivity. J Urol. 2011 Dec;186(6):2470-7. PMID: 22019173.
Barkin J. Review of dutasteride/tamsulosin fixed-dose combination for the treatment of benign prostatic hyperplasia: efficacy, safety, and patient acceptability. Patient Prefer Adherence. 2011;5:483-90. PMID: 22003286.
Rajpathy J, Aswathaman K, Sinha M, et al. An in vitro study on human ureteric smooth muscle with the alpha1-adrenoceptor subtype blocker, tamsulosin. BJU Int. 2008 Dec;102(11):1743-5. PMID: 18778345.