Description
Tazobactam is a β-lactamase inhibitor that is clinically used to enhance the antibacterial efficacy of β-lactam antibiotics. Tazobactam is especially active against Enterobacter and Staphylococcus.
Product Unit Size | Cost | Quantity | Stock |
---|
Tazobactam is a β-lactamase inhibitor that is clinically used to enhance the antibacterial efficacy of β-lactam antibiotics. Tazobactam is especially active against Enterobacter and Staphylococcus.
Cas No. | 89786-04-9 |
---|---|
Purity | ≥98% |
Formula | C10H12N4O5S |
Formula Wt. | 300.29 |
Chemical Name | (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1- ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide |
IUPAC Name | (2S,3S,5R)-3-methyl-4,4, 7-trioxo-3-(triazol-1-ylmethyl)-4λ6-thia-1-azabicyclo[3.2.0]heptane- 2-carboxylic acid |
Synonym | YTR-830H, CL-298741 |
Melting Point | 170-178°C |
Solubility | water, methanol |
Appearance | White Crystal Powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.
Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.
Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.
Calcium channel blocker.
Fermentation impurity
Building block
NS3/4A inhibitor
Endogenous peptide hormone, involved in intesti...
Nucleoside (guanosine) analog; RT, guanylyl cyc...
Imidazole; HMG-CoA reductase, 14-α demethylase...
Proteasome inhibitor, miR33b modulator.
RORα/γ inverse agonist.
Triterpene sapogenin found in species of Panax;...
Low osmolarity contrast agent used for imaging ...
Fluoroquinolone; vacuolar H+ ATPase, topoisomer...
Thiazolidinedione; PPARγ agonist.
Aureothricin is a member of the dithiolopyrrolo...
Side chain attached to various taxanes.
SIRT1/2 inhibitor, indirect p53 activator.
Peptide, casein fragment.
Mast cell stabilizer; TRPV2 antagonist, PDGFR i...
Aza-anthracenedione, DNA intercalator; topoisom...
Steroid; glucocorticoid agonist.