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Thiamphenicol is a chloramphenicol analog that exhibits antibiotic activity. Thiamphenicol inhibits the 50S subunit of the bacterial ribosome, inhibiting protein translation. Thiamphenicol displays antibacterial efficacy against Streptococcus, Staphylococcus, Escherichia, and Haemophilus.
| Cas No. | 52628-58-7 |
|---|---|
| Purity | ≥98% |
| Formula | C28H45Cl2NO6S |
| Formula Wt. | 594.63 |
| IUPAC Name | [(1R,2R)-2-[(2, 2-dichloroacetyl)amino]-3-hydroxy-1-(4-methylsulfonylphenyl)propyl] hexadecanoate |
| Melting Point | 108-112°C |
| Appearance | Yellowish-Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Raymond J, Boutros N, Bergeret M. Role of thiamphenicol in the treatment of community-acquired lung infections. Med Trop (Mars). 2004;64(1):33-8. PMID: 15224555.
Marchese A, Debbia EA, Tonoli E, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14(6):554-61. PMID: 12583545.