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Tolmetin Sodium

Tolmetin Sodium

Product ID T5944
Cas No. 64490-92-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $53.80 In stock
5 g $152.70 In stock
25 g $554.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tolmetin is a pyrrole non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory and analgesic activities. Tolmetin inhibits COX-1 and COX-2, preventing prostaglandin E (PGE) production; it is clinically used to treat rheumatoid arthritis and osteoarthritis.

Product Info

Cas No.

64490-92-2

Purity

≥98%

Formula

C15H14NNaO3 • 2H2O

Formula Wt.

315.30

Chemical Name

1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid sodium salt dihydrate

IUPAC Name

sodium;2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetate

Synonym

Tolmetin sodium salt dihydrate, Reutol, Tolectine, Tolmene

Melting Point

155-157 (dec.)

Solubility

Soluble in water.

Appearance

Off-white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T5944 MSDS PDF

Info Sheet

T5944 Info Sheet PDF

References

Fernandes E, Costa D, Toste SA, et al. In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs. Free Radic Biol Med. 2004 Dec 1;37(11):1895-905. PMID: 15528048.

Davies J, Dixon AS, Steele CE. Tolmetin sodium and indomethacin in the treatment of osteoarthrosis of the hip: a double-blind crossover study. Curr Med Res Opin. 1980;7(2):115-20. PMID: 7002480.

Cordrey LJ. Tolmetin sodium, a new anti-arthritis drug: double-blind and long-term studies. J Am Geriatr Soc. 1976 Oct;24(10):440-6. PMID: 61224.

Custom Order

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