| Product Unit Size | Cost | Quantity | Stock |
|---|
Trimebutine exhibits antibacterial and gastrointestinal motility modulating activities; it is clinically used to treat irritable bowel syndrome (IBS). Trimebutine displays antibiotic activity against Escherichia and Pseudomonas. This compound enhances gastrointestinal muscle contractions by inhibiting L-type Ca2+ channels and decreasing Ca2+-sensitive (BK) K+ currents and may also act as an agonist at opioid receptors.
| Cas No. | 39133-31-8 |
|---|---|
| Purity | ≥97% |
| Formula | C22H29NO5 |
| Formula Wt. | 387.47 |
| Chemical Name | Benzoic acid, 3,4,5-trimethoxy-, 2-(dimethylamino)-2- phenylbutyl ester |
| IUPAC Name | [2-(dimethylamino)-2-phenylbutyl] 3,4,5-trimethoxybenzoate |
| Synonym | EINECS 254-309-2 |
| Melting Point | 78-80°C |
| Solubility | Soluble in methylene chloride. |
| Appearance | White Crystal Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Kountouras J, Sofianou D, Gavalas E, et al. Trimebutine as a potential antimicrobial agent: a preliminary in vitro approach. Hippokratia. 2012 Oct;16(4):347-9. PMID: 23935315.
Tan W, Zhang H, Luo HS, et al. Effects of trimebutine maleate on colonic motility through Ca²+-activated K+ channels and L-type Ca²+ channels. Arch Pharm Res. 2011 Jun;34(6):979-85. PMID: 21725819.