• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
URB597

URB597

Product ID U682040
Cas No. 546141-08-6
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $57.20 In stock
25 mg $193.30 In stock
100 mg $565.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

URB597 is an inhibitor of fatty acid amide hydrolase (FAAH). FAAH inhibition leads to an increase of anandamide, a naturally occurring substrate for the cannabinoid receptors. Increase in anandamide and activation of the CB receptors decreases sensitivity to pain in rat models. Additionally, URB597 also decreases the amount of tyrosine hydrolase in neurons in a CB receptor/FAAH independent manner. URB597 also demonstrates an anti-neuroinflammatory effect in Sprague-Dawley rat models. URB597 shows analgesic effects in numerous pain models

Product Info

Cas No.

546141-08-6

Purity

≥98%

Formula

C20H22N2O3

Formula Wt.

338.41

Chemical Name

Cyclohexylcarbamic acid 3´-carbamoyl-biphenyl-3-yl ester

IUPAC Name

[3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate

Solubility

50mM in DMSO

Appearance

White powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

U682040 MSDS PDF

Info Sheet

U682040 Info Sheet PDF

References

Murphy N, Cowley TR, Blau CW et al. The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation. J Neuroinflammation. 2012 Apr 26;9:79. PMID: 22537429.

Bosier B, Muccioli GG, and Lamber DM. The FAAH inhibitor URB597 efficiently reduces tyrosine hydroxylase expression through CB1 and FAAH-independent mechanisms. Br J Pharmacol. 2013 Jun;169(4):794-807. PMID: 22970888

Kwilasz AJ, Abdullah RA, Poklis JL et al. Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats. Behav Pharmacol. 2014 Apr;25(2):119-29. PMID: 24583930

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G5875

    Gossypol Acetic Acid

    Bcl-2, Bcl-xl, sialyl transferase inhibitor.

    ≥98%
  • K1978

    Ketorolac Tromethamine

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • R3220

    Rifampicin

    Ansamycin; bacterial DNA-dependent RNA polymera...

    ≥98%
  • P3540

    PIK-75 Hydrochloride

    p110α PI3K inhibitor.

    ≥98%
  • T5720

    Tofacitinib Citrate

    JAK1/2/3 inhibitor.

    ≥99%
  • S3345

    Silymarin

    Flavonolignan mixture found in Silybum (milk th...

    ≥50% sylibin
  • I761004

    Itaconic Acid

    Polymer precursor

    ≥99%
  • A5133

    Amiloride Hydrochloride Dihydrate

    K+-sparing diuretic; ENaC and acid-sensing ion ...

    ≥98%
  • F4881

    Flumequine Sodium

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • C1878

    Cetrimide

    Mixture of quaternary ammonium salts, cationic ...

    ≥98%
  • R1876

    all-trans-Retinol

    Diterpene component of vitamin A, differentiati...

    ≥95%
  • C000171

    C-171

    STING inhibitor

    ≥98%
  • C3263

    Ciprofloxacin Hydrochloride Monohydrate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • F4502

    Flavokawain A

    Chalcone kavalactone found in Piper methysticum...

    ≥98%
  • N5770

    Norfloxacin Hydrochloride

    First generation fluoroquinolone antibiotic.

    ≥98%
  • P2400

    Phenethyl Caffeate

    Found in propolis; 5-lipoxygenase inhibitor.

    ≥98%
  • H2980

    Humanin, human

    Endogenous peptide; FPRL1/2 agonist.

    ≥95%
  • C104761

    CCT-196969

    pan-Raf inhibitor.

    ≥98%
  • V3378

    Vitamin B12

    Coenzyme, vitamin found in dairy, meat, eggs, f...

    ≥97%
  • H0207

    Hepatitis B Virus Core Protein (128-140)

    B cell epitope found on hepatitis B viral core ...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only