LKT Labs

Biochemicals for Life Science Research

Verbascoside

Verbascoside

Product ID V1869
Cas No. 61276-17-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $127.90 In stock
5 mg $245.30 In stock
10 mg $367.30 In stock
25 mg $714.70 In stock
Bulk Quote

Quicklinks

Description

Verbascoside is a phenylpropanoid found in a variety of species of Castilleja, Verbena, and Verbascum. Verbascoside displays anti-inflammatory, analgesic, antioxidative, and antithrombotic properties in a variety of cellular and animal models. In vitro, verbascoside inhibits arachidonic acid- and ADP-induced platelet aggregation as well as dipeptidyl peptidase 4 (DPP4) and prolyl oligopeptidase activity. In vivo, verbascoside decreases levels of Bax, Bcl-2, NF-κB, iNOS, and myeloperoxidase, showing anti-inflammatory benefit in a model of periodontitis. Additionally, this compound inhibits mechanical pain in two different animal models of hyperalgesia. Verbascoside may also be an inhibitor of PKC.

Product Info

Cas No.

61276-17-3
Purity

≥98%
Formula

C29H36O15

Formula Wt.

624.59
Chemical Name

[(2R,3R,4R,5R,6R)-6-[2-(3, 4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R, 6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
IUPAC Name

[(2R,3R,4R,5R,6R)-6-[2-(3, 4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R, 6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Synonym

Acteoside, Kusaginin
Appearance

Off-white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

V1869 MSDS PDF
Info Sheet

V1869 Info Sheet PDF

References

Campo G, Marchesini J, Bristot L, et al. The in vitro effects of verbascoside on human platelet aggregation. J Thromb Thrombolysis. 2012 Oct;34(3):318-25. PMID: 22723176.

Filho AG, Morel AF, Adolpho L, et al. Inhibitory effect of verbascoside isolated from Buddleja brasiliensis Jacq. ex Spreng on prolyl oligopeptidase activity. Phytother Res. 2012 Oct;26(10):1472-5. PMID: 22275311.

Paola RD, Oteri G, Mazzon E, et al. Effects of verbascoside, biotechnologically purified by Syringa vulgaris plant cell cultures, in a rodent model of periodontitis. J Pharm Pharmacol. 2011 May;63(5):707-17. PMID: 21492173.

Isacchi B, Iacopi R, Bergonzi MC, et al. Antihyperalgesic activity of verbascoside in two models of neuropathic pain. J Pharm Pharmacol. 2011 Apr;63(4):594-601. PMID: 21401613.

Kahraman C, Tatli II, Orhan IE, et al. Cholinesterase inhibitory and antioxidant properties of Verbascum mucronatum Lam. and its secondary metabolites. Z Naturforsch C. 2010 Nov-Dec;65(11-12):667-74. PMID: 21319708.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • L8008

    D-Luciferin, firefly, Free Acid

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • S3470

    Sirtinol

    Sirtuin inhibitor and iron chelator.

    ≥98%
  • E7378

    Estrone

    Endogenous steroid hormone, estriol precursor; ...

    ≥97%
  • B8278

    Butoconazole Nitrate

    Imidazole; 14-α demethylase inhibitor.

    ≥98%
  • V9228

    VX-765

    NLRP3 and caspase-1 inhibitor.

    ≥98%
  • G1209

    GDC-0980

    PI3K and mTOR inhibitor.

    ≥98%
  • I058584

    Ibotenic Acid

    Analog of glutamate

    ≥98%
  • T0253

    Tangeretin

    Polymethoxy flavonoid found in citrus fruits.

    ≥98%
  • S5200

    SNA 1

    Sialic-acid sensing lectin.

    ≥98%
  • M1677

    11-Methoxyyangonin

    Minor kavalactone originally found in Piper met...

    ≥98%
  • L8278

    Luteinizing Hormone Releasing Hormone, salmon

    Endogenous peptide hormone, involved in secreti...

    ≥95%
  • P3269

    Piroxicam

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • N859614

    NVP-LDE225

    Smo inhibitor.

    ≥98%
  • E325127

    EIDD-1931

    Broad-spectrum antiviral activity against SARS-...

    ≥99%
  • C2468

    β-Calcitonin Gene Related Peptide, human

    Endogenous calcitonin-family peptide, involved ...

    ≥98%
  • P7058

    Protocatechuic Aldehyde

    Polyphenol found in various plants and foods.

    ≥98%
  • C3250

    Cimetidine

    Histamine H2 and AR antagonist, catalase inhibi...

    ≥99%
  • C1600

    Carcinoembryonic Antigen (605-613)

    Carcinoembryonic antigen epitope.

    ≥95%
  • G7342

    GSK-2126458

    p110α PI3K and mTOR inhibitor.

    ≥99%
  • T3039

    Thienyloctyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥97%