• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Wogonoside

Wogonoside

Product ID W5727
Cas No. 51059-44-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $102.00 In stock
10 mg $153.10 In stock
25 mg $275.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Wogonoside is a flavonoid glycoside found in the Scutellaria plant; it displays anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities. In vitro, wogonoside decreases levels of nitrous oxide (NO) and prostaglandin E2 (PGE2) and inhibits release of pro-inflammatory cytokines TNF-α and IL-6. Wogonoside also increases p21 and decreases c-Myc, ERK1/2, and p38 MAPK expression in vitro, inducing cell cycle arrest and autophagy in a variety of cancer cell lines. Wogonoside inhibits vessel growth and migration in vitro and in vivo, decreasing phosphorylation of JNK, ERK, and p38 MAPK.

Product Info

Cas No.

51059-44-0

Purity

≥98%

Formula

C22H20O11

Formula Wt.

460.39

Chemical Name

(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(5-hydroxy-8-methoxy-4-oxo-2-phenylchromen-7-yl)oxyoxane-2-carboxylic acid

IUPAC Name

(2S,3S,4S,5R,6S)-3,4, 5-trihydroxy-6-(5-hydroxy-8-methoxy-4-oxo-2-phenylchromen-7-yl)oxyoxane- 2-carboxylic acid

Synonym

Oroxindin

Appearance

Light Yellow Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

W5727 MSDS PDF

Info Sheet

W5727 Info Sheet PDF

References

Yang YZ, Tang YZ, Liu YH. Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells. J Ethnopharmacol. 2013 Jun 21;148(1):271-6. PMID: 23612420.

Chen Y, Hui H, Yang H, et al. Wogonoside induces cell cycle arrest and differentiation by affecting expression and subcellular localization of PLSCR1 in AML cells. Blood. 2013 May 2;121(18):3682-91. PMID: 23487022.

Sun Y, Zou M, Hu C, et al. Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway. Food Chem Toxicol. 2013 Jan;51:53-60. PMID: 23000445.

Chen Y, Lu N, Ling Y, et al. Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction. Toxicology. 2009 May 2;259(1-2):10-7. PMID: 19428938.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • L0284

    Lavendustin A

    Tyrosine kinase inhibitor.

    ≥97%
  • K0117

    Kaempferol

    Flavonol found in various plant sources.

    ≥98%
  • G3352

    Ginkgolic Acid (13:0)

    Alkylphenol found in Ginkgo; HIV protease inhib...

    ≥98%
  • C1627

    Cefaclor Monohydrate

    β-lactam cephalosporin; penicillin binding pro...

    ≥97%
  • J6400

    (+)-JQ-1

    Triazolothienodiazepine; BRD inhibitor.

    ≥99%
  • T0096

    Cephalomannine

    Diterpene found in Taxus; potential microtubule...

    ≥98%
  • P7012

    Prednisolone Sodium Phosphate

    Water-soluble cortisol derivative; glucocortico...

    ≥98%
  • D5992

    Doxapram Hydrochloride Hydrate

    K+ channel blocker, catecholamine release stimu...

    ≥98%
  • D1628

    5,6-Dehydrokawain

    Kavalactone originally found in Piper methystic...

    ≥98%
  • A7668

    Atracurium Besylate

    Non-depolarizing NMJ blocker; AChR antagonist.<...

    ≥95%
  • P3568

    Pirarubicin

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • M4100

    MK-0524

    DP1 antagonist.

    ≥99%
  • S1069

    Scriptaid

    HDAC inhibitor.

    ≥98%
  • P6852

    Propafenone Hydrochloride

    β-adrenergic antagonist, Kv1.4 and K2P2 K+ cha...

    ≥98%
  • D1643

    Delta Sleep Inducing Peptide

    Peptide; GABA potentiator, NMDA negative allost...

    ≥95%
  • I4000

    Ikarugamycin

    Protein translation inhibitor.

    ≥98%
  • E6256

    Epothilone A

    Microtubule depolymerization inhibitor.

    ≥95%
  • S8007

    Substance P (1-7)

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • K0276

    Katacalcin

    Peptide found in crustaceans; PKA activator.

    ≥95%
  • A1592

    ADX-47273

    mGluR5 positive modulator.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only