Description
WS6 is an activator of islet β cell proliferation that also stimulates α cell proliferation. WS6 displays potential anti-diabetic activity, normalizing blood glucose levels.
WS6
Product ID W7201
Cas No. 1421227-53-3
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
|---|
Product Info
| Cas No. | 1421227-53-3 |
|---|---|
| Purity | ≥98% |
| Formula | C29H31F3N6O3 |
| Formula Wt. | 568.60 |
| Chemical Name | 4-[[6-[(Cyclopropylcarbonyl)amino]-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzeneacetamide |
| IUPAC Name | N-(6-{4-[2-({4-[(4-Methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}amino)-2-oxoethyl]phenoxy}-4-pyrimidinyl)cyclopropanecarboxamide |
| Solubility | DMSO 100 mg/mL Ethanol 100 mg/mL Water Insoluble |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
|---|---|
| Info Sheet |
References
Boerner BP, George NM, Mir SU, et al. WS6 induces both alpha and beta cell proliferation without affecting differentiation or viability. Endocr J. 2015;62(4):379-86. PMID: 25739404.
Shen W, Tremblay MS, Deshmukh VA, et al. Small-molecule inducer of β cell proliferation identified by high-throughput screening. J Am Chem Soc. 2013 Feb 6;135(5):1669-72. Erratum in: J Am Chem Soc. 2013 Mar 20;135(11):4573. PMID: 23330637.