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Y-320

Y-320

Product ID Y0002
Cas No. 288250-47-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $112.60 In stock
5 mg $211.10 In stock
10 mg $379.70 In stock
25 mg $759.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Y-320 is a phenylpyrazoleanilide that inhibits IL-17 production by CD4+ T cells, preventing the development and progression of arthritis in animal models. This compound displays immunomodulatory and anti-inflammatory activities.

Product Info

Cas No.

288250-47-5

Purity

≥98%

Formula

C27H29ClN6O2

Formula Wt.

505.02

Chemical Name

1-(4-Chlorophenyl)-N-{3-cyano-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl}-5-methyl-1H-pyrazole-4-carboxamide

IUPAC Name

1-(4-Chlorophenyl)-N-{3-cyano-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl}-5-methyl-1H-pyrazole-4-carboxamide

Synonym

Y320

Solubility

DMSO 11 mg/mL (21.78 mM) Water Insoluble Ethanol Insoluble

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

Y0002 MSDS PDF

Info Sheet

Y0002 Info Sheet PDF

References

Ushio H, Ishibuchi S, Oshita K, et al. A new phenylpyrazoleanilide, y-320, inhibits interleukin 17 production and ameliorates collagen-induced arthritis in mice and cynomolgus monkeys. Pharmaceuticals (Basel). 2013 Dec 23;7(1):1-17. PMID: 24366113.

Chiba K. A new orally active anti-rheumatic drug targets IL-15 and IL-17. Nihon Rinsho Meneki Gakkai Kaishi. 2007 Oct;30(5):375-82. PMID: 17984577.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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