• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
(−)-Epicatechin Gallate

(−)-Epicatechin Gallate

Product ID E6232
Cas No. 1257-08-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $52.20 In stock
5 mg $173.60 In stock
25 mg $510.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

(-)-Epicatechin gallate (ECG) is a flavanol/catechin originally found in Camilla and other plan sources; it exhibits antioxidative, neuromodulatory, anticancer, and anti-inflammatory activities. ECG displays agonist activity at cannabinoid 1 (CB1) receptors. ECG also inhibits expression of FLT3 and decreases phosphorylation of p38 MAPK, Akt, and STAT5 in acute myelogenous leukemia (AML) cells, suppressing cell proliferation. In vitro, this compound inhibits LPS- or peptidoglycan-induced production of VEGF and expression of COX-2.

Product Info

Cas No.

1257-08-5

Purity

≥98%

Formula

C22H18O10

Formula Wt.

442.37

Chemical Name

3,4,5-Trihydroxybenzoic acid, (2R,3R)-3,4- dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2-H-1-benzopyran-3-yl ester

IUPAC Name

[(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate

Synonym

ECG

Melting Point

218°C

Solubility

Soluble in water or alcohol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E6232 MSDS PDF

Info Sheet

E6232 Info Sheet PDF

Brochures

Green Tea Flyer

Brochures

Natural Products Booklet

References

Nakanishi T, Mukai K, Hosokawa Y, et al. Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells. Int Endod J. 2014 May 21. [Epub ahead of print]. PMID: 24847951.

Ly BT, Chi HT, Yamagishi M, et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. PLoS One. 2013 Jun 20;8(6):e66378. PMID: 23840454.

Korte G, Dreiseitel A, Schreier P, et al. Tea catechins' affinity for human cannabinoid receptors. Phytomedicine. 2010 Jan;17(1):19-22. PMID: 19897346.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C2945

    Chlorophyllin Sodium-Copper Salt

    Semi-synthetic derivative of chlorophyll; food ...

    USP 28
  • B1979

    Betulinic Acid

    Pentacyclic triterpene.

    ≥99%
  • B0396

    BAY80-6946

    p110α PI3K inhibitor.

    ≥98%
  • V3476

    Vitamin D2

    Vitamin D prodrug produced by fungi and alfalfa...

    ≥91%
  • T1002

    2-Debenzoyl Paclitaxel-2-(2-Methyl-2-Butenoate)

    Synthesis intermediate

    ≥95%
  • U698578

    Urolithin C

    Ellagic acid derivative produced by gut microfl...

    ≥98%
  • H9815

    25-Hydroxyvitamin D3

    Vitamin D, calcitriol prodrug; VDR agonist.

    ≥98%
  • M9634

    Myriocin

    Atypical amino acid found in Isaria sinclairi, ...

    ≥99%, TLC
  • I0480

    Ibudilast

    PDE3/5 inhibitor, LTD4 antagonist.

    ≥98%
  • M2077

    1-Methoxy-5-methylphenazinium Methyl Sulfate

    Electron carrier used to study dehydrogenase el...

    ≥98%
  • T0118

    7-epi-Cephalomannine

    Cephalomannine derivative found in Taxus; poten...

    ≥95%
  • S8147

    Sulindac Sulfide

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • A5135

    Aminophylline Dihydrate

    Xanthine derivative; adenosine antagonist, PDE ...

    ≥98%
  • N344786

    N-Nitroso Valsartan Methyl Ester

    Valsartan impurity

  • N8760

    NVP-TAE684

    ALK, c-Fes, LRRK2 inhibitor.

    ≥98%
  • L0249

    Laminin Peptide YIGSR-NH2

    Laminin-derived peptapeptide.

    ≥98%
  • C7997

    C-Type Natriuretic Peptide (1-22), human

    Endogenous cardiomodulatory peptide; NPR-B agon...

    ≥95%
  • A5161

    Ampiroxicam

    Piroxicam prodrug, NSAID; COX-1/2 inhibitor.

    ≥98%
  • D3219

    Diflubenzuron

    Benzoylurea, insect growth regulator; chitin sy...

    ≥95%
  • B030964

    BAY-1816032

    BUB1 inhibitor.

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only