LKT Labs

Biochemicals for Life Science Research

Levamisole Hydrochloride

Levamisole Hydrochloride

Product ID L1682
Cas No. 16595-80-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $61.00 In stock
10 g $102.00 In stock
Bulk Quote

Quicklinks

Description

Levamisole is an imidazothiazole that exhibits immunomodulatory, anti-parasitic, anti-helminthic, anti-angiogenic, and anticancer chemotherapeutic activities. Levamisole inhibits alkaline phosphatase and may act as an agonist at nicotinic acetylcholine receptors (nAChRs). In multiple myeloma cells, levamisole induces DNA fragmentation, cytochrome c release and caspase 3 activation, inhibiting cellular proliferation. In other models, levamisole also inhibits proliferation and differentiation of endothelial cells and suppresses growth of various tumors in vivo.

Product Info

Cas No.

16595-80-5
Purity

≥98%
Formula

C11H12N2S • HCl
Formula Wt.

240.76
Chemical Name

Imidazo(2,1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI)

IUPAC Name

(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1, 3]thiazole;hydrochloride
Synonym

Tetramisole hydrochloride, Citarin L, Ergamisol, Spartakon
Melting Point

228-230°C
Solubility

Soluble in water.

Appearance

A white or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

L1682 MSDS PDF
Info Sheet

L1682 Info Sheet PDF

References

Ramanadham M, Nageshwari B. Anti-proliferative effect of levamisole on human myeloma cell lines in vitro. J Immunotoxicol. 2010 Oct-Dec;7(4):327-32. PMID: 20860474.

Friis T, Engel AM, Klein BM, et al. Levamisole inhibits angiogenesis in vitro and tumor growth in vivo. Angiogenesis. 2005;8(1):25-34. PMID: 16132615.

Zinser EW, Wolf ML, Alexander-Bowman SJ, et al. Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals. J Vet Pharmacol Ther. 2002 Aug;25(4):241-50. PMID: 12213111.

Van Belle H. Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22(7):972-6. PMID: 6169.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • I5212

    Indirubin

    Bisindole isomer of indigo found in Indigo natu...

    ≥98%
  • T5060

    TMP-269

    HDAC inhibitor.

    ≥98%
  • T0102

    7-epi-Taxol

    Taxane found in Taxus; potential microtubule de...

    ≥95%
  • I7259

    Isoproterenol Hydrochloride

    β-adrenergic agonist.

    ≥98%
  • C1644

    Celecoxib

    NSAID; COX-2 inhibitor.

    ≥99%
  • C0221

    Caffeine

    Xanthine alkaloid found in coffee, tea, and oth...

    ≥98%
  • L589921

    Loxapine Succinate

    D2 and D4 dopamine receptor inhibitor.

    ≥99%
  • C0365

    Carvedilol

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • C8501

    CV-66

    1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...

    ≥60%
  • S3346

    Silodosin

    α1A-adrenergic antagonist.

    ≥98%
  • C4000

    CK-636

    Arp2/3 inhibitor.

    ≥98%
  • T6803

    Trandolapril

    ACE inhibitor.

    ≥98%
  • B1973

    Besifloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • T0153

    Tanshinone I

    Diterpene found in Salvia.

    ≥95%
  • N344786

    N-Nitroso Valsartan Methyl Ester

    Valsartan impurity

    ≥98%
  • S1059

    Scopolamine Hydrobromide Trihydrate

    Tropane alkaloid found in Solanaceae plants; M1...

    ≥98%
  • P3269

    Piroxicam

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • M185777

    4-(Methylsulfinyl) butylamine

    ≥99%
  • R0161

    Rapamycin

    Macrolide originally produced by Streptomyces; ...

    ≥99%
  • B5560

    B-type Natriuretic Peptide (1-32), rat

    Endogenous cardiomodulatory peptide; NPR-A agon...

    ≥95%