LKT Labs

Biochemicals for Life Science Research

Levamisole Hydrochloride

Levamisole Hydrochloride

Product ID L1682
Cas No. 16595-80-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $61.00 In stock
10 g $102.00 In stock
Bulk Quote

Quicklinks

Description

Levamisole is an imidazothiazole that exhibits immunomodulatory, anti-parasitic, anti-helminthic, anti-angiogenic, and anticancer chemotherapeutic activities. Levamisole inhibits alkaline phosphatase and may act as an agonist at nicotinic acetylcholine receptors (nAChRs). In multiple myeloma cells, levamisole induces DNA fragmentation, cytochrome c release and caspase 3 activation, inhibiting cellular proliferation. In other models, levamisole also inhibits proliferation and differentiation of endothelial cells and suppresses growth of various tumors in vivo.

Product Info

Cas No.

16595-80-5
Purity

≥98%
Formula

C11H12N2S • HCl
Formula Wt.

240.76
Chemical Name

Imidazo(2,1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI)

IUPAC Name

(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1, 3]thiazole;hydrochloride
Synonym

Tetramisole hydrochloride, Citarin L, Ergamisol, Spartakon
Melting Point

228-230°C
Solubility

Soluble in water.

Appearance

A white or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

L1682 MSDS PDF
Info Sheet

L1682 Info Sheet PDF

References

Ramanadham M, Nageshwari B. Anti-proliferative effect of levamisole on human myeloma cell lines in vitro. J Immunotoxicol. 2010 Oct-Dec;7(4):327-32. PMID: 20860474.

Friis T, Engel AM, Klein BM, et al. Levamisole inhibits angiogenesis in vitro and tumor growth in vivo. Angiogenesis. 2005;8(1):25-34. PMID: 16132615.

Zinser EW, Wolf ML, Alexander-Bowman SJ, et al. Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals. J Vet Pharmacol Ther. 2002 Aug;25(4):241-50. PMID: 12213111.

Van Belle H. Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22(7):972-6. PMID: 6169.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E5358

    Enoxacin

    Fluoroquinolone; vacuolar H+ ATPase, topoisomer...

    ≥98%
  • S6232

    Spiramycin

    Macrolide; protein synthesis inhibitor. ≥3900...

    ≥3900 IU/mg
  • G3558

    20R-Ginsenoside Rh2

    Triterpene saponin found in Panax.

    ≥98%
  • C5863

    Coptisine Chloride, natural

    Isoquinoline alkaloid found in a variety of pla...

    ≥98%
  • A5059

    Amoxapine

    5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenerg...

    ≥98%
  • C3251

    Cinnarizine

    FIASMA, L-type Ca2+ channel blocker, D2 antagon...

    ≥98%
  • S8146

    Sulindac Sulfone

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • B4976

    BMS-794833

    MET, VEGFR2, Ron, Axl, FLT3 inhibitor.

    ≥98%
  • B8174

    Butylated Hydroxyanisole

    Commercial food additive, antioxidant.

    ≥96%
  • O2146

    R-(+)-Ofloxacin

    Fluoroquinolone, optically active isomer of ofl...

    ≥98%
  • G4483

    Glucagon-like Peptide II, human

    Endogenous peptide hormone, involved in intesti...

    ≥95%
  • L920000

    LX-2343

    Promotes Aβ clearance.

    ≥98%
  • U682040

    URB597

    FAAH inhibitor.

    ≥98%
  • S4932

    SMI-4a

    Thiazolidine; Pim kinase inhibitor.

    ≥99%
  • Y0052

    Yangonin

    Dienolide kavalactone originally found in Piper...

    ≥98%
  • L0254

    Lansoprazole

    H+/K+ ATPase inhibitor.

    ≥98%
  • L1735

    Levitide

    Antimicrobial peptide found in amphibians.

    ≥95%
  • C0245

    Calcitonin Gene Related Peptide, rat

    Endogenous calcitonin-family peptide, involved ...

    ≥95%
  • D5898

    Doxycycline Monohydrate

    Tetracycline; protein translation inhibitor, MM...

    ≥97%
  • D3232

    3,3′-Diindolylmethane

    Indole found in cruciferous vegetables; AhR ago...

    ≥98%