LKT Labs

Biochemicals for Life Science Research

CNX-774

CNX-774

Product ID C5592
Cas No. 1202759-32-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $54.00 In stock
5 mg $118.00 In stock
25 mg $391.00 In stock
Bulk Quote

Quicklinks

Description

CNX-774 inhibits Bruton’s tyrosine kinase (BTK) and displays potential anticancer and immunosuppressive activities.

Product Info

Cas No.

1202759-32-7
Purity

≥98%
Formula

C26H22FN7O3
Formula Wt.

499.50
Chemical Name

4-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]-N-methylpyridine-2-carboxamide
IUPAC Name

4-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]-N-methylpyridine-2-carboxamide
Synonym

CNX774
Solubility

DMSO 100 mg/mL (200.2 mM) Ethanol 2 mg/mL (4.0 mM) Water Insoluble

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

C5592 MSDS PDF
Info Sheet

C5592 Info Sheet PDF

References

Akinleye A, Chen Y, Mukhi N, et al. Ibrutinib and novel BTK inhibitors in clinical development. J Hematol Oncol. 2013 Aug 19;6:59. PMID: 23958373.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F8048

    Fumagillin

    Produced by Aspergillus; type 2 methionine amin...

    ≥98%
  • M9367

    Myricetin

    Flavonol found in fruits and vegetables; COMT i...

    ≥98%
  • D022705

    Darunavir

    HIV and AIDS

    ≥99%
  • K1776

    Ketotifen Fumarate

    H1 histamine and LT antagonist, PDE inhibitor.<...

    ≥98%
  • N3450

    Nimesulide

    NSAID; COX-2 inhibitor.

    ≥98%
  • M5756

    Montelukast Sodium

    CysLT1 antagonist.

    ≥98%
  • M1678

    2-Methoxyestradiol

    Estradiol metabolite; microtubule depolymerizat...

    ≥98%
  • C1635

    Ceftazidime Hydrate

    β-lactam cephalosporin; penicillin binding pro...

    ≥97%
  • T2833

    1-Thio-β-D-glucose Tetraacetate

    Imaging agent; Maillard reaction inhibitor.

    ≥98%
  • L0250

    Laminin Peptide SIKVAV

    Laminin-derived hexapeptide.

    ≥98%
  • D760022

    DT-2216

    BCL-XL specific degrader

    ≥98%
  • M0272

    Mastoparan 7

    Antimicrobial peptide found in bee and wasp ven...

    ≥95%
  • T5946

    Toltrazuril

    Coccidiostat; mitochondrial respiration inhibit...

    ≥98%
  • H9613

    N-(4-Hydroxyphenyl)retinamide

    Retinol (vitamin A) analog, binds RBP4; Des1 in...

    ≥98%
  • T1028

    Paclitaxel, 8-Hydro-bicyclo(3.3.0)octane

    Synthesis impurity

    ≥95%
  • D1994

    Dexrazoxane

    Iron chelator.

    ≥98%
  • A7202

    AS-604850

    p110γ PI3K inhibitor.

    ≥98%
  • S7600

    Staurosporine

    Alkaloid produced by Streptomyces, precursor in...

    ≥98%
  • A081014

    Acalabrutinib

    Inhibitor of Bruton’s tyrosine kinase (BTK).<...

    ≥99%
  • B5000

    BMS-911543

    JAK2 inhibitor.

    ≥99%