LKT Labs

Biochemicals for Life Science Research

Ramipril

Ramipril

Product ID R0249
Cas No. 87333-19-5
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $67.80 In stock
500 mg $127.90 In stock
1 g $225.40 In stock
5 g $631.20 In stock
Bulk Quote

Quicklinks

Description

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that exhibits anti-arrhythmic, antihypertensive, and cardioprotective activities. In animal models of myocardial infarction, ramipril decreases ventricular tachycardia and ventricular fibrillation. In other, similar animal models, ramipril increases antioxidative enzyme activity, improving left ventricular ejection fraction and inhibiting left ventricular remodeling. Ramipril is clinically used to treat high blood pressure, congestive heart failure (CHF), and diabetic neuropathy.

Product Info

Cas No.

87333-19-5
Purity

≥98%
Formula

C23H32N2O5
Formula Wt.

416.51
Chemical Name

[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]octahydrocyclo- penta[b]pyrrole-2-carboxylic acid
IUPAC Name

(2S,3aS, 6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
Synonym

Tritace, Ramace, Unipril, Vesdil
Melting Point

109°C
Solubility

Soluble in DMSO (10mg/mL).and Acetonitrile
Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

R0249 MSDS PDF
Info Sheet

R0249 Info Sheet PDF

References

Zhong Y, Cao P, Tong C, et al. Effect of ramipril on the electrophysiological characteristics of ventricular myocardium after myocardial infarction in rabbits. J Cardiovasc Med (Hagerstown). 2012 May;13(5):313-8. PMID: 22441218.

Chen CY, Lee BC, Hsu HC, et al. A proteomic study of the effects of ramipril on post-infarction left ventricular remodelling in the rabbit. Eur J Heart Fail. 2008 Aug;10(8):740-8. PMID: 18583185.

Dupuis F, Atkinson J, Limiñana P, et al. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens. 2005 May;23(5):1061-6. PMID: 15834293.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • W5727

    Wogonoside

    Flavonoid glycoside found in Scutellaria.

    ≥98%
  • F4557

    Floxuridine

    5-Fluorouracil derivative, fluorinated pyrimidi...

    ≥98%
  • N3276

    Nitroso(acetoxymethyl)methylamine

    NNK precursor found in tobacco smoke; carcinoge...

    ≥97%
  • V5886

    Voriconazole

    Triazole; 14α demethylase inhibitor.

    ≥98%
  • I7556

    1-Isothiocyanato-7-(methylsulfonyl)-heptane

    ITC, erysolin analog.

    ≥98%
  • D6958

    Droloxifene Citrate

    Tamoxifen analog; SERM.

    ≥98%
  • P6004

    PP-242

    Dual mTORC1/mTORC2 inhibitor.

    ≥98%
  • F1992

    Fexaramine

    FXR agonist.

    ≥98%
  • A5001

    Aminopterin

    Folic acid analog, derivative of pterin; dihydr...

    ≥98%
  • N3584

    Nivalenol

    Trichothecene mycotoxin produced by Fusarium; p...

    ≥98%
  • U7354

    Usnic Acid

    Dibenzofuran produced by lichens.

    ≥98%
  • P0092

    Paclitaxel, from Taxus yunnanensis

    Diterpene found in Taxus yunnanensis; microtubu...

    ≥98%
  • E2002

    Efaroxan Hydrochloride

    α2-adrenergic and imidazoline-1 antagonist, AT...

    ≥99%
  • G1652

    Genistein

    Phytoestrogen, isoflavone found in various plan...

    ≥98%
  • U6956

    Uroguanylin, human

    Endogenous peptide, involved in water/Na+ homeo...

    ≥95%
  • H2980

    Humanin, human

    Endogenous peptide; FPRL1/2 agonist.

    ≥95%
  • C864760

    CVT-313

    Selective CDK2 inhibitor.

    ≥98%
  • T3357

    Tioconazole

    Imidazole; 14-α demethylase inhibitor.

    ≥98%
  • T1010

    7-Acetyl Paclitaxel

    Synthesis impurity

    ≥98%
  • C822706

    Curvularin

    Macrocyclic lactone.

    ≥98%