Description
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
Product Unit Size | Cost | Quantity | Stock |
---|
BAY-1082439 is an inhibitor of PI3K. It is selective for the PI3Kα/β/δ isoforms. In vivo, BAY-1082439 has shown efficacy in inhibiting PTEN-null prostate cancer growth.
Cas No. | 1375469-38-7 |
---|---|
Purity | ≥98% |
Formula | C25H30N6O5 |
Formula Wt. | 494.55 |
IUPAC Name | N-{8-[(2R)-2-Hydroxy-3-(4-morpholinyl)propoxy]-7-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl}-2-methylnicotinamide |
Synonym | BAY 1082439, BAY1082439, BAY10-82439, BAY 10-82439, BAY-10-82439 |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Zou Y., Qi Z., et al. Cotargeting the Cell-Intrinsic and Microenvironment Pathways of Prostate Cancer by PI3Kα/β/δ Inhibitor BAY1082439. Mol Cancer Ther. 17(10):2091-99 (2018). PMID: 30045927.
Bisphosphonate; inhibits transfer of farnesyl p...
Dihydropyridine, FIASMA; L-type Ca2+ channel bl...
Quinazoline; α1-adrenergic antagonist.
PKA substrate.
Rapamycin analog
ATR inhibitor.
Isothiocyanate found in cruciferous vegetables,...
Peptide, vasopressin analog; V1/2 agonist.
β2-adrenergic agonist, potential ENaC activato...
MET, VEGFR2, Ron, Axl, FLT3 inhibitor.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
GPR84 agonist.
Amino acid precursor of dopamine.
Diphenylmethane derivative, stimulates colonic ...
Synthetic cytokinin, plant growth regulator; fi...
Polymethoxylated flavone found in citrus fruits...
Polyphenol found in Camilla sinensis; HIV integ...
Hydrazine; L-amino acid decarboxylase inhibitor...
Selective inhibitor of the γ isoform of PI3K (...
Nrf2-Keap1-ARE complex activator.