• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ketorolac Tromethamine

Ketorolac Tromethamine

Product ID K1978
Cas No. 74103-07-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $50.50 In stock
5 g $188.70 In stock
25 g $754.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory and analgesic activities. Ketorolac inhibits COX-1 and COX-2. In vivo, administration of ketorolac prevents the spinal injury-induced increase of protease-activated receptor 1 (PAR1) levels and decreases activation of spinal astrocytes, resulting in decreased allodynia. In spinal neurons, ketorolac decreases substance P-, calcitonin gene-related peptide- and dynorphin-immunoreactivity. Additionally, this compound decreases expression of phosphodiesterase type 4 (PDE4D).

Product Info

Cas No.

74103-07-4

Purity

≥98%

Formula

C15H13NO3 • C4H11NO3

Formula Wt.

376.40

Chemical Name

2-amino-2-(hydroxymethyl)propane-1,3-diol;5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

IUPAC Name

2-amino-2-(hydroxymethyl)propane-1,3-diol;5-benzoyl-2, 3-dihydro-1H-pyrrolizine-1-carboxylic acid

Synonym

Toradol, Acular

Melting Point

165-167°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

K1978 MSDS PDF

Info Sheet

K1978 Info Sheet PDF

References

Dong L, Smith JR, Winkelstein BA. Ketorolac reduces spinal astrocytic activation and PAR1 expression associated with attenuation of pain after facet joint injury. J Neurotrauma. 2013 May 15;30(10):818-25. PMID: 23126437.

Bendixen KH, Baad-Hansen L, Cairns BE, et al. Effects of low-dose intramuscular ketorolac on experimental pain in the masseter muscle of healthy women. J Orofac Pain. 2010 Fall;24(4):398-407. PMID: 21197512.

Wang XM, Hamza M, Gordon SM, et al. COX inhibitors downregulate PDE4D expression in a clinical model of inflammatory pain. Clin Pharmacol Ther. 2008 Jul;84(1):39-42. PMID: 18288087.

Ma W, Eisenach JC. Intraplantar injection of a cyclooxygenase inhibitor ketorolac reduces immunoreactivities of substance P, calcitonin gene-related peptide, and dynorphin in the dorsal horn of rats with nerve injury or inflammation. Neuroscience. 2003;121(3):681-90. PMID: 14568028.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N1721

    Nefiracetam

    Pyrrolidone; NMDA and mGluR5 agonist, N-type an...

    ≥98%
  • T5769

    Toremifene Base

    SERM, androgen modulator.

    ≥98%
  • A044178

    Abemaciclib mesylate

    CDK inhibitor.

    ≥98%
  • B8174

    Butylated Hydroxyanisole

    Commercial food additive, antioxidant.

    ≥96%
  • H1794

    Hexamethonium Bromide Hydrate

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • R3586

    Rivastigmine Tartrate

    AChE and BChE inhibitor.

    ≥99%
  • O4102

    Okadaic Acid Ammonium

    Shellfish toxin produced by dinoflagellates and...

    ≥98%
  • N2400

    NG-52

    Purine, purvalenol A analog; CDK2, Cdc28p, Pho8...

    ≥98%
  • Q8134

    Quinapril Hydrochloride

    ACE inhibitor.

    ≥98%
  • A5133

    Amiloride Hydrochloride Dihydrate

    K+-sparing diuretic; ENaC and acid-sensing ion ...

    ≥98%
  • T6831

    Triadimenol

    Triadimefon metabolite; mutagen.

    ≥96%
  • L283080

    LHC-165

    TLR7 agonist

    ≥99%
  • T8000

    Tubacin

    HDAC6 inhibitor.

    ≥96%
  • A5228

    Angiogenin

    Small protein, cleaves RNA.

    ≥98%
  • H9714

    L-5-Hydroxytryptophan

    Endogenous amino acid, precursor of 5-HT and me...

    ≥98%
  • P8167

    Puromycin Aminonucleoside

    Purine nucleoside analog; DNA chain terminator,...

    ≥98%
  • K5604

    Kobe 0065

    Ras inhibitor.

    ≥99%
  • T2934

    Thiamphenicol Palmitate

    Chloramphenicol derivative; protein translation...

    ≥98%
  • E7657

    Etoposide

    Podophyllotoxin derivative; topoisomerase II in...

    ≥98%
  • N1868

    Neratinib

    EGFR inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only