LKT Labs

Biochemicals for Life Science Research

Glycitin

Glycitin

Product ID G4799
Cas No. 40246-10-4
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $132.60 In stock
25 mg $592.30 In stock
Bulk Quote

Quicklinks

Description

Glycitin is a glycosylated isoflavone found in soy that activates bitter taste receptors (TAS2Rs). Glycitin exhibits anticancer chemotherapeutic and anti-osteoporotic properties. Glycitin inhibits the expression of matrix metalloproteinases 3 and 9 and suppresses invasive activity of glioma cells in vitro. Glycitin also exhibits effects on bone formation. This compound increases proliferation of mouse bone marrow stromal cells and osteoblasts and inhibits adipogenesis of bone marrow stromal cells as well as adipocytic transdifferentiation of osteoblasts. Like glycitein, this compound may act as a phytoestrogen.

Product Info

Cas No.

40246-10-4
Purity

≥98%
Formula

C22H22O10
Formula Wt.

446.40
Chemical Name

3-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
IUPAC Name

3-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Synonym

Glycitein 7-O-glucoside
Solubility

Soluble in DMSO poorly; insoluble in other solvents
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

G4799 MSDS PDF
Info Sheet

G4799 Info Sheet PDF

References

Roland WS, Vincken JP, Gouka RJ, et al. Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39. J Agric Food Chem. 2011 Nov 9;59(21):11764-71. PMID: 21942422.

Lee EJ, Kim SY, Hyun JW, et al. Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression. Chem Biol Interact. 2010 Apr 15;185(1):18-24. PMID: 20188714.

Li XH, Zhang JC, Sui SF, et al. Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts. Acta Pharmacol Sin. 2005 Sep;26(9):1081-6. PMID: 16115375.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R2512

    RGD

    Tripeptide, binds cell surface integrins.

    ≥95%
  • C446176

    Clemastine Fumarate

    Antihistamine with potential neuroprotective ac...

    ≥99%
  • B8276

    Butyric Acid Sodium

    HDAC inhibitor, RNA splicing modulator.

    ≥98%
  • V1868

    Veratramine

    Steroidal alkaloid found in Veratrum and Fritil...

    ≥98%
  • F285081

    Fidaxomicin

    Macrocycle

    ≥98%
  • R2513

    RGDS

    Tetrapeptide, binds cell surface integrins.

    ≥95%
  • T1014

    7-TES-Paclitaxel

    Synthesis impurity

    ≥95%
  • M0113

    Madecassoside

    Triterpenoid found in Centella.

    ≥90%
  • D5612

    2-n-Dodecylfuran

    Furan derivative.

    ≥98%
  • A7577

    Astilbin

    Flavonoid found in various plant sources.

    ≥99%
  • D3300

    (Z)-1,-Bis(2-methoxy-5-(trifluoromethyl)phenyl)diazene oxide

    Azoxy compound

    ≥98%
  • T8020

    Tuftsin

    Tetrapeptide, IgG Fc region derivative; Nrp1 ag...

    ≥95%
  • N3474

    Nisoldipine

    Calcium channel blocker.

    ≥98%
  • M0126

    Magainin 2

    Antimicrobial peptide found in frogs, induces p...

    ≥95%
  • C5662

    Copper Bis-3,5-diisopropylsalicylate

    Antioxidant.

    ≥97%
  • A528251

    Angiotensin I/II (1-7)(DP-7)

    Peptide fragment

    ≥95%
  • R5992

    Roxithromycin

    Macrolide; protein synthesis inhibitor.

    ≥96%
  • S1607

    Secretin, rat

    Endogenous peptide hormone, involved in feeding...

    ≥95%
  • P6956

    Prostaglandin E1

    Endogenous prostaglandin, vasodilator.

    ≥98%
  • M1669

    6-Mercaptopurine Monohydrate

    Thiopurine antimetabolite; PRPP amidotransferas...

    ≥98%