LKT Labs

Biochemicals for Life Science Research

Etomidate

Etomidate

Product ID E7758
Cas No. 33125-97-2
Purity ≥99%
Product Unit SizeCostQuantityStock
10 mg $127.70 In stock
25 mg $255.30 In stock
100 mg $728.80 In stock
Bulk Quote

Quicklinks

Description

Etomidate activates GABA-A receptors, displaying neuromodulatory, anesthetic, and amnestic activities. Etomidate prevents neurotransmitter release in neurons by inhibiting presynaptic excitatory synaptic transmission in a SNARE-dependent manner. Etomidate also attenuates acetylcholine-induced relaxation in aortic endothelial tissue, but does not display significant cardiovascular side effects when used clinically. In animal models, etomidate impairs memory performance in several tasks.

Product Info

Cas No.

33125-97-2
Purity

≥99%
Formula

C14H16N2O2
Formula Wt.

244.29
IUPAC Name

ethyl 3-[(1R)-1-phenylethyl]imidazole-4-carboxylate
Synonym

Amidate
Solubility

DMSO: >10 mg/mL
Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

E7758 MSDS PDF
Info Sheet

E7758 Info Sheet PDF

References

Herring BE, McMillan K, Pike CM, et al. Etomidate and propofol inhibit the neurotransmitter release machinery at different sites. J Physiol. 2011 Mar 1;589(Pt 5):1103-15. Erratum in: J Physiol. 2011 Sep 15;589(Pt 18):4633. PMID: 21173083.

Martin LJ, Oh GH, Orser BA. Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade. Anesthesiology. 2009 Nov;111(5):1025-35. PMID: 19809285.

Sohn JT, Kim HJ, Cho HC, et al. Effect of etomidate on endothelium-dependent relaxation induced by acetylcholine in rat aorta. Anaesth Intensive Care. 2004 Aug;32(4):476-81. PMID: 15682522.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E537335

    Enniatin B1

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • R9632

    Recombinant Zika Virus NS1 Antigen

    Zika Virus antigen
  • A5281

    Angiotensin II (4-8), human

    Endogenous peptide fragment, involved in vasoco...

    ≥95%
  • I7155

    Isoindigo

    Potential AhR binding agent.

    ≥98%
  • M0368

    Marbofloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • T1004

    Paclitaxel Oxetane Ring-Opened 3-Acetyl 4-Benzoyl Impurity

    Synthesis impurity

    ≥92%
  • G4634

    Glipizide

    Sulfonylurea; ATP-sensitive K+ channel blocker....

    ≥98%
  • A724092

    Asciminib Hydrochloride

    Allosteric inhibitor

    ≥98%
  • I0480

    Ibudilast

    PDE3/5 inhibitor, LTD4 antagonist.

    ≥98%
  • N5550

    Nomilin

    Triterpene found in species of Citrus; HIV-1 pr...

    ≥98%
  • M1749

    Memantine Hydrochloride

    D2 agonist, NMDA, 5-HT3, α7 nAChR antagonist.<...

    ≥97%
  • T0093

    2′-Acetyltaxol

    Taxane synthesis intermediate.

    ≥98%
  • D170310

    10,11-Dehydrocurvularin

    Fungal metabolite produced by Penicillium speci...

    ≥98%
  • S771339

    STING Agonist-12

    STING activator

    ≥99%
  • S0254

    Sanguinarine Chloride

    Decreases expression of MMPs, PGE2, and COX-2, ...

    ≥98%
  • T1968

    Terpinen-4-ol

    Monoterpene found in various plant sources.

    ≥98%
  • M1622

    Mefenamic Acid

    NSAID; GABA-A potentiator, COX-1/2 inhibitor.

    ≥98%
  • A0910

    N-Acetyl-S-(N′-phenylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant.

    ≥98%
  • C2948

    Chloroadenosine

    Nucleoside (adenosine) analog; DNA chain termin...

    ≥98%
  • C5768

    Corazonin

    Neuropeptide found in insects.

    ≥95%