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4-Thiouridine

Product ID T2933
Cas No. 13957-31-8
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $61.30 In stock
25 mg $148.70 In stock
100 mg $480.40 In stock
250 mg $971.80 In stock
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  • Description
  • Product Info
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

4-Thiouridine is a modified nucleotide that induces DNA cross-linking after irradiation with UV light. This compound is often used for labeling DNA in research models.

Product Info

Cas No.

13957-31-8

Purity

≥98%

Formula

C9H12N2O5S

Formula Wt.

260.27

Chemical Name

Uridine, 4-thio- (8CI)(9CI)

IUPAC Name

1-[3, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one

Synonym

Thiouridine

Melting Point

141-143°C

Solubility

Soluble in water (20 mg/mL), ethanol (2 mg/mL), DMSO (10 mg/mL).

Appearance

Yellowish crystalline powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T2933 MSDS PDF

Info Sheet

T2933 Info Sheet PDF

References

Wang L, Ruffner DE. An ultraviolet crosslink in the hammerhead ribozyme dependent on 2-thiocytidine or 4-thiouridine substitution. Nucleic Acids Res. 1997 Nov 1;25(21):4355-61. PMID: 9336468.

Ofengand J, Liou R, Kohut J 3rd, et al. Covalent cross-linking of transfer ribonucleic acid to the ribosomal P site. Mechanism and site of reaction in transfer ribonucleic acid. Biochemistry. 1979 Oct 2;18(20):4322-32. PMID: 385051.

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