Description
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
| Cas No. | 58131-57-0 |
|---|---|
| Purity | ≥98% |
| Formula | C11H13N5O4 |
| Formula Wt. | 279.25 |
| Chemical Name | Benzofurazan, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
| IUPAC Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
| Synonym | NSC207895; NSC 207895; NSC-207895; NSC 179940 |
| Solubility | DMSO 0.4 mg/mL (1.43 mM) Water Insoluble Ethanol Insoluble |
| Appearance | Orange to red solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wang H, Ma X, Ren S, et al. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther. 2011 Jan;10(1):69-79. PMID: 21075910.
HEXIM1 activator.
Cationic lipid polypeptide, mixture of polymyxi...
STING agonist
Indoloquinazoline alkaloid found in Evodia; COX...
Cholesterol ester transfer protein inhibitor.
NSAID; NMDA inverse agonist, T-type Ca2+ and Cl...
Ca2+ ATPase and ATP-sensitive K+ channel activa...
PDGFR inhibitor.
Inhibitor of Bcl-2 and Bcl-xL
Allosteric inhibitor
GSK-3β inhibitor.
Tetracycline; protein translation inhibitor, MM...
Protease inhibitor.
β-lactam; penicillin binding protein inhibitor...
Naphthoquinone found in Plumbago.
p110α PI3K and mTOR inhibitor.
Melatonin analog; MT1/2 agonist.
FAK inhibitor.