LKT Labs

Biochemicals for Life Science Research

Vitexin

Vitexin

Product ID V344766
Cas No. 3681-93-4
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $45.00 In stock
25 mg $147.00 In stock
100 mg $421.00 In stock
Bulk Quote

Quicklinks

Description

Vitexin is a naturally occurring flavonoid found in hawthorn leaves. Treatment of diabetic rats with vitexin has been found to result in pancreatic islet regeneration, prevention of beta-cell destruction, and suppression of lipopolysaccharide-induced release of HMGB1 protein. Pretreatment of neonatal C57BL/6 mice with vitexin provided neuroprotection against hypoxic-ischemic brain injury. In addition, vitexin is has shown anti-oxidant, anti-inflammatory, analgesic, and antitumor activities in several cancer models and cell lines. It has been found to impact the JNK MAPK signaling pathway to inhibit growth of hepatocellular carcinoma cells.

Product Info

Cas No.

3681-93-4
Purity

≥98%
Formula

C21H20O10
Formula Wt.

432.38
Chemical Name

5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
IUPAC Name

5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
Synonym

Apigenin-8-C-glucoside, Vitxein
Solubility

Soluble in water and in DMSO
Appearance

Off white to yellow

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

V344766 MSDS PDF
Info Sheet

V344766 Info Sheet PDF

References

Nurdiana S, Goh YM, Ahmad H, et al. Changes in pancreatic histology, insulin secretion and oxidative status in diabetic rats following treatment with Ficus deltoidea and vitexin. BMC Complement Altern Med. 2017 Jun 2;17(1):290. PMID: 28576138.

Wang F, Yin J, Ma Y, et al. Vitexin alleviates lipopolysaccharide-induced islet cell injury by inhibiting HMGB1 release. Mol Med Rep. 2017 Mar;15(3):1079-1086. PMID: 28098903.

Min JW, Kong WL, Han S, et al. Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain. Oncotarget. 2017 Apr 11;8(15):25513-25524. PMID: 28424420.

He JD, Wang Z, Li SP, et al. Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway. Oncotarget. 2016 Dec 20;7(51):84520-84532. PMID: 27588401.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5276

    Angiotensin I, human

    Endogenous peptide, cleavage product of angiote...

    ≥98%
  • P6901

    Pramipexole Dihydrochloride

    D2/3 agonist.

    ≥98%
  • S8009

    Substance P (7-11)

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • L283080

    LHC-165

    TLR7 agonist

    ≥99%
  • G4597

    18β-Glycyrrhetinic Acid

    Triterpene glycoside found in Glycyrrhiza; 15-H...

    ≥98%
  • V1869

    Verbascoside

    Phenylpropanoid found in Castilleja, Verbena, V...

    ≥98%
  • G8225

    Guggulsterone

    Steroid found in myrrh; FXR antagonist.

    ≥98%
  • M3598

    Mizoribine Hydrobromide

    IMPDH inhibitor.

    ≥98%
  • S520011

    SN-011

    STING antagonist

    ≥97%
  • A5031

    4-Aminophenylphosphate Disodium

    Alkaline phosphatase substrate used to quantify...

    ≥98%
  • F1670

    Ferulic Acid Methyl Ester

    Hydroxycinnamic aicd, verbascoside metabolite, ...

    ≥98%
  • H6225

    HPGDS-inhibitor-1

    HPGDS inhibitor.

    ≥98%
  • O4658

    Olopatadine Hydrochloride

    Mast cell stabilizer; histamine H1/2/3 antagoni...

    ≥99%
  • B6801

    Brassinin

    Phytoalexin, indole found in cruciferous vegeta...

    ≥98%
  • A4935

    6-Aminocaproic Acid

    Protease inhibitor.

    ≥98%
  • D1770

    Dermorphin Analog

    Synthetic peptide; dermorphin analog; δOR and ...

    ≥95%
  • R580665

    Roquefortine C

    Mycotoxin produced by various fungi including t...

    ≥98%
  • V3345

    Vildagliptin

    DPP4 inhibitor.

    ≥98%
  • N1984

    Neuropeptide FF

    Endogenous RF-amide peptide, involved in nocice...

    ≥95%
  • L186860

    Levomefolic acid calcium salt

    Folic acid derivative

    ≥98%