Vitexin

Name: Vitexin
SKU: V344766
Availability: InStock

Product ID V344766

Cas No. 3681-93-4

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Vitexin is a naturally occurring flavonoid found in hawthorn leaves. Treatment of diabetic rats with vitexin has been found to result in pancreatic islet regeneration, prevention of beta-cell destruction, and suppression of lipopolysaccharide-induced release of HMGB1 protein. Pretreatment of neonatal C57BL/6 mice with vitexin provided neuroprotection against hypoxic-ischemic brain injury. In addition, vitexin is has shown anti-oxidant, anti-inflammatory, analgesic, and antitumor activities in several cancer models and cell lines. It has been found to impact the JNK MAPK signaling pathway to inhibit growth of hepatocellular carcinoma cells.

Product Info

Cas No.	3681-93-4
Purity	≥98%
Formula	C₂₁H₂₀O₁₀
Formula Wt.	432.38
Chemical Name	5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
IUPAC Name	5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
Synonym	Apigenin-8-C-glucoside, Vitxein
Solubility	Soluble in water and in DMSO
Appearance	Off white to yellow

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	V344766 MSDS PDF
Info Sheet	V344766 Info Sheet PDF

References

Nurdiana S, Goh YM, Ahmad H, et al. Changes in pancreatic histology, insulin secretion and oxidative status in diabetic rats following treatment with Ficus deltoidea and vitexin. BMC Complement Altern Med. 2017 Jun 2;17(1):290. PMID: 28576138.

Wang F, Yin J, Ma Y, et al. Vitexin alleviates lipopolysaccharide-induced islet cell injury by inhibiting HMGB1 release. Mol Med Rep. 2017 Mar;15(3):1079-1086. PMID: 28098903.

Min JW, Kong WL, Han S, et al. Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain. Oncotarget. 2017 Apr 11;8(15):25513-25524. PMID: 28424420.

He JD, Wang Z, Li SP, et al. Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway. Oncotarget. 2016 Dec 20;7(51):84520-84532. PMID: 27588401.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Vitexin

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

7-Methyl-6-mercaptopurine

Betamethasone

Terbutaline Sulfate

BAY80-6946

MRTX1719

Colistin Sulfate

Leptomycin B

Roquefortine C

Nigericin Sodium

Ceftriaxone Disodium Hemiheptahydrate

PPQ-102

5-Aminopyrimidine

Acalabrutinib

Cisplatin

R-(−)-Iberin

Hyaluronic Acid Sodium (0.2 -5 kDA)

Anethole Trithione

Polygalic Acid

Retinyl Acetate

Latrunculin A

Footer