LKT Labs

Biochemicals for Life Science Research

Cytarabine

Cytarabine

Product ID C9778
Cas No. 147-94-4
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $52.00 In stock
500 mg $139.00 In stock
1 g $225.00 In stock
Bulk Quote

Quicklinks

Description

Cytarabine is a cytosine nucleoside analog that exhibits anticancer chemotherapeutic and antiviral activities. This antimetabolite is clinically used to treat chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), and non-Hodgkin lymphoma. Cytarabine inhibits RNA polymerase and DNA polymerase, preventing DNA synthesis. Although it is too toxic for antiviral use, cytarabine inhibits the growth or replication of herpesviruses such as varicella-zoster and cytomegalovirus (CMV).

Product Info

Cas No.

147-94-4
Purity

≥98%
Formula

C9H13N3O5
Formula Wt.

243.22
Chemical Name

4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
IUPAC Name

4-amino-1-[(2R,3S,4S,5R)-3, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonym

Alexan, Arabitin, Ara-C, Cytosar, Erpalfa, Iretin, Udicil
Melting Point

212-213°C
Solubility

Soluble in water to 100 mM, DMSO to 50 mM, ethanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

C9778 MSDS PDF
Info Sheet

C9778 Info Sheet PDF

References

Abdel-Aziz W, Jiang HY, Hickey RJ, et al. Ara-C affects formation of cancer cell DNA synthesome replication intermediates. Cancer Chemother Pharmacol. 2000;45(4):312-9. PMID: 10755320.

Hiddemann W. Cytosine arabinoside in the treatment of acute myeloid leukemia: the role and place of high-dose regimens. Ann Hematol. 1991 Apr;62(4):119-28. PMID: 2031974.

Lauter CB, Bailey EJ, Lerner AM. Assessment of cytosine arabinoside as an antiviral agent in humans. Antimicrob Agents Chemother. 1974 Nov;6(5):598-602. PMID: 15825312.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F4782

    Fludarabine Phosphate

    Nucleoside (adenosine) analog; DNA chain termin...

    ≥98%
  • A4444

    L-Alliin

    Cysteine derivative found in Allium; NMDA NR2A/...

    ≥98%
  • D582703

    Dorsomorphin

    Inhibitor of ALK2, ALK3, ALK6, and AMPK.

    ≥98%
  • R1724

    Regadenoson

    Adenosine A2A agonist.

    ≥99%
  • F4680

    Flutamide

    Non-steroid; AR antagonist.

    ≥98%
  • M1685

    Mevastatin

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • H1657

    Heparin-binding Peptide

    Peptide, binds heparin.

    ≥95%
  • A464766

    Altenuene

    Alternaria mycotoxin which may be found in food...

    ≥98%
  • K3352

    Kinetensin

    Peptide, neurotensin analog.

    ≥95%
  • C4559

    Clomiphene Citrate

    Used for in vitro fertilization; FIASMA, SERM.<...

    ≥98%
  • F4400

    Flag Peptide

    Peptide, used to tag proteins for affinity chro...

    ≥95%
  • P6958

    Protopanaxatriol

    Triterpene sapogenin found in species of Panax;...

    ≥95%
  • O610291

    Ophiobolin A

    Tetracyclic sesterpenoid phytotoxin.

    ≥98%
  • K0022

    K252b

    Staurosporine analog; PKC inhibitor.

    ≥98%
  • A5035

    5-Aminosalicylic Acid

    Salicylic acid derivative; PPARγ agonist, pote...

    ≥98%
  • M7200

    MS436

    BRD4 inhibitor.

    ≥99%
  • P7021

    Prednisone Acetate

    Synthetic prednisolone prodrug; glucocorticoid ...

    ≥98%
  • V5725

    Voglibose

    α-glucosidase inhibitor, potential GLP-1 agoni...

    ≥99%
  • A1319

    Adenosine Triphosphate Disodium Hydrate

    Endogenous coenzyme, unit of cellular energy, r...

    ≥95%
  • D0808

    DCC-2036

    Abl inhibitor.

    ≥98%