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α-Conotoxin IMI

α-Conotoxin IMI

Product ID C5656
Cas No. 156467-85-5
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $102.90 Please Inquire
1 mg $173.30 Please Inquire
2.5 mg $341.30 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

α-Conotoxin IMI is a peptide inhibitor of α7 nicotinic acetylcholine receptors (nAChRs) originally found in species of Conus snails. α-Conotoxin IMI disrupts motor coordination, inhibiting the swimming ability of leeches. Like other conotoxins, α-conotoxin IMI binds the interface between different subunits of nAChRs.

Product Info

Cas No.

156467-85-5

Purity

≥95%

Formula

C52H78N20O15S4

Formula Wt.

1351.56

Solubility

Soluble in 20% acetonitrile (1 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C5656 MSDS PDF

Info Sheet

C5656 Info Sheet PDF

References

Yu R, Craik DJ, Kaas Q. Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. PLoS Comput Biol. 2011 Mar;7(3):e1002011. PMID: 21390272.

Wagenaar DA, Gonzalez R, Ries DC, et al. Alpha-conotoxin ImI disrupts central control of swimming in the medicinal leech. Neurosci Lett. 2010 Nov 26;485(3):151-6. PMID: 20833225.

Ellison M, McIntosh JM, Olivera BM. Alpha-conotoxins ImI and ImII. Similar alpha 7 nicotinic receptor antagonists act at different sites. J Biol Chem. 2003 Jan 10;278(2):757-64. PMID: 12384509.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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