• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
α-Tocotrienol

α-Tocotrienol

Product ID T5608
Cas No. 58864-81-6
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $71.50 In stock
5 mg $200.10 In stock
10 mg $357.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tocotrienols contain an arene ring, a chromanol ring, and an isoprenoid tail; all tocotrienol compounds contain a methyl group on C8 of the arene ring.
α-Tocotrienol contains two additional methyl groups arranged around the arene ring, positioned para and ortho to C8. Tocotrienols are members of the vitamin E family, typically found in vegetable oils, nuts, and grains. All tocotrienols exhibit strong antioxidative, anti-angiogenic, anticancer, and anti-hyperlipidemic qualities, although α-Tocotrienol displays the strongest antioxidative capacity. Tocopherols, common substituents of over-the-counter vitamin E supplements, interfere with tocotrienol activity and show weaker antioxidative effects. Tocotrienols exhibit significant radical recycling abilities in cellular models of lipid peroxidation and oxidative damage and suppress HMG-CoA reductase activity. In vitro, these compounds induce apoptosis through inhibition of Id1, EGFR, and NF-κB; they also inhibit vessel formation and proliferation in aortic endothelial cells.

Product Info

Cas No.

58864-81-6

Purity

≥98%

Formula

C29H44O2

Formula Wt.

424.66

IUPAC Name

(2R)-2,5,7,8-tetramethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7, 11-trienyl]-3,4-dihydrochromen-6-ol

Synonym

alpha-tocotrienol

Solubility

Soluble in ethanol, hexanes, DMSO, DMF

Appearance

yellow liquid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T5608 MSDS PDF

Info Sheet

T5608 Info Sheet PDF

References

Yap WN, Chang PN, Han HY, et al. Gamma-tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways. Br J Cancer. 2008 Dec 2;99(11):1832-41. PMID: 19002171.

Sen CK, Khanna S, Roy S. Tocotrienols: Vitamin E beyond tocopherols. Life Sci. 2006 Mar 27;78(18):2088-98. PMID: 16458936.

Inokuchi H, Hirokane H, Tsuzuki T, et al. Anti-angiogenic activity of tocotrienol. Biosci Biotechnol Biochem. 2003 Jul;67(7):1623-7. PMID: 12913317.

Parker RA, Pearce BC, Clark RW, et al. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993 May 25;268(15):11230-8. PMID: 8388388.

Serbinova E, Kagan V, Han D, et al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic Biol Med. 1991;10(5):263-75. PMID: 1649783.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S7769

    Streptomycin Sulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • T0098

    10-Deacetyltaxol C

    Diterpene found in Taxus; potential microtubule...

    ≥97%
  • A4845

    Amylin (8-37), rat

    Endogenous peptide hormone inolved in gastric e...

    ≥95%
  • N4524

    NLG919

    Indoleamine-2,3-dioxygenase inhibitor.

    ≥98%
  • T3036

    Thienylhexyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥97%
  • O7053

    L-Ornithine Hydrochloride

    Non-proteinogenic amino acid, L-arginine metabo...

    ≥98%
  • A5170

    Amrinone

    Pyridine; PDE3 inhibitor.

    ≥98%
  • A9978

    Aztreonam

    β-lactam; penicillin binding protein inhibitor...

    ≥96%
  • S6019

    Speract

    Peptide, derived from egg outer envelope; K+ ch...

    ≥95%
  • T0102

    7-epi-Taxol

    Taxane found in Taxus; potential microtubule de...

    ≥95%
  • A5302

    Anastrozole

    Aromatase inhibitor.

    ≥99%
  • N3476

    Nitisinone

    Nitrobenzene; HPPD inhibitor.

    ≥99%
  • D8145

    Duloxetine Hydrochloride

    SERT and NET inhibitor, Nav1.7 Na+ channel bloc...

    ≥99%
  • B3209

    Bicalutamide

    AR antagonist.

    ≥98%
  • A016493

    4-Aminopyrimidine

    Building block

    ≥98%
  • E7357

    Esomeprazole Potassium

    (S) isomer of omeprazole; H+/K+ ATPase and MAO-...

    ≥98%
  • R1724

    Regadenoson

    Adenosine A2A agonist.

    ≥99%
  • E6846

    Erlotinib Hydrochloride

    EGFR inhibitor.

    ≥98%
  • D1760

    3-Acetyl-deoxynivalenol

    Type A trichothecene mycotoxin produced by Fusa...

    ≥98%
  • G4597

    18β-Glycyrrhetinic Acid

    Triterpene glycoside found in Glycyrrhiza; 15-H...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only