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α-Zearalenol

α-Zearalenol

Product ID Z161024
Cas No. 36455-72-8
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $170.40 In stock
5 mg $613.20 In stock
10 mg $1,083.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

α-Zearalenol is a mycotoxin that has structural similarity to estrogen and can bind to estrogen receptors. α-Zearalenol is one of the major metabolites of zearalenone, which is produced by several species of Fusarium and is known to induce many toxic effects. In cultured cells, α-Zearalenol was shown to inhibit cell viability, protein and DNA syntheses, and to induce oxidative damage.

Product Info

Cas No.

36455-72-8

Purity

≥98%

Formula

C18H24O5

Formula Wt.

320.39

IUPAC Name

(4~{S},8~{R},12~{E})-8,16,18-trihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraen-2-one

Synonym

Alpha-Zearalenol; Trans-Zearalenol; Cis-Zearalenol; Zearalenol; (3R,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one; 1H-2-benzoxacyclotetradecin-1-one, 3,4,5,6,7,8,9,10-octahydro-7,14,16-trihydroxy-3-methyl-, (3S,7R,11E)-; 3,4,5,6,7,8,9,10-octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

Z161024 MSDS PDF

Info Sheet

Z161024 Info Sheet PDF

References

Tatay E, Espin S, Garcia-Fernandez AJ, et al. Estrogenic activity of zearalenone, α-Zearalenol and β-Zearalenol assessed using the E-screen assay in MCF-7 cells. Toxicol Mech Methods. 2018 May;28(4):239-242. PMID: 29057713.

Ben Salem I, Boussabbeh M, Pires Da Silva J, et al. SIRT1 protects cardiac cells against apoptosis induced by zearalenone or its metabolites α-Zearalenol and β-Zearalenol through an autophagy-dependent pathway. Toxicol Appl Pharmacol. 2017 Jan 1;314:82-90. PMID: 27889531.

Othmen ZO, Golli EE, Abid-Essefi S, et al. Cytotoxicity effects induced by zearalenone metabolites, alpha zearalenol and beta zearalenol, on cultured Vero cells. Toxicology. 2008 Oct 30;252(1-3):72-77. PMID: 18755238.

Custom Order

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