β-Cembrenediol, an anti-cancer and anti-proliferative agent, is one of the cembrenediols diterpenes originally found in Anisomeles. These compounds exhibit antibacterial activity against Mycobacterium and antifungal activity against Colletotrichum.
Cembrenoids accumulated in tobacco exhibit potent antiproliferative activity and trigger unusual microtubule dynamics in human glioblastoma cells.
β-cembrenediol effectively inhibited the root and stem growth of receptor plants and the inhibitory effects was concentration-dependent. Seedlings of lettuce (Tai Yuan Sun) were treated with β-cembrenediol and the results showed that β-cembrenediol significantly inhibited the seedling growth and reduced fresh weight of L. sativa. The compounds effectively affected cell mitotic index and caused cell death.