• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
β-Endorphin, human

β-Endorphin, human

Product ID E5217
Cas No. 61214-51-5
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $245.30 Please Inquire
2 mg $417.10 In stock
5 mg $735.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

β-Endorphin is an endogenous opioid peptide that acts as an agonist at μ-opioid receptors (μORs) and exhibits immunomodulatory, neuromodulatory, antidepressant, and antinociceptive/analgesic activities. In vivo, β-endorphin increases levels of B-cells and production of antibodies as well as secretion of IL-4 and proliferation of spleenocytes, shifting the immune response toward Th2-specific mediators. This peptide, like other endogenous opioids, plays a significant role in reward and reinforcement signaling, especially in brain regions such as the ventral tegmental area (VTA) and nucleus accumbens (NAcc). β-Endorphin release is induced during exercise and shows antidepressant activity in clinical studies.

Product Info

Cas No.

61214-51-5

Purity

≥95%

Formula

C158H251N39O46S

Formula Wt.

3465.06

Synonym

β-Lipotropin (61-91), human; β-Lipotropin C-fragment; LPH (61-91).

Solubility

Soluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E5217 MSDS PDF

Info Sheet

E5217 Info Sheet PDF

References

Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

Gein SV, Baeva TA, Nebogatikov VO, et al. β-Endorphin effects on antibody production, proliferation, and secretion of Th1/Th2 cytokines in vivo. Bull Exp Biol Med. 2012 Mar;152(5):595-9. PMID: 22803142.

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E5222

    Endothelin-3, human

    Endogenous peptide, involved in vascular contra...

    ≥95%
  • C1660

    CEP-32496

    V600E B-Raf inhibitor.

    ≥98%
  • E2542

    Met-Enkephalin Amide

    Endogenous opioid peptide; δOR and μOR agonis...

    ≥95%
  • D0004

    Dabrafenib

    B-Raf and c-Raf inhibitor.

    ≥98%
  • D0261

    Dapivirine

    RT inhibitor.

    ≥98%
  • D3372

    Disodium Cycloheptylaminomethylene Diphosphate

    Bisphosphonate; squalene synthase inhibitor.

    ≥98%
  • C4534

    Clindamycin Palmitate Hydrochloride

    Lincosamide; ribosomal translocation and protei...

    ≥98%
  • M1644

    Meloxicam

    NSAID; COX-2 inhibitor.

    ≥98%
  • T1953

    Tenovin-3

    Potential p53 activator or SIRT2 inhibitor.

    ≥98%
  • A7461

    Asperosaponin VI

    Triterpene saponin found in Dipsacus asper.

    ≥98%
  • P2856

    Phorbol-12,13-dibutyrate

    PKC and PKD activator, carcinogen.

    ≥98%
  • B7973

    Busulfan

    Alkyl sulfonate; DNA alkylator.

    ≥98%
  • T6817

    D(+)-Trehalose Dihydrate

    α-Linked disaccharide composed of α-glucose u...

    ≥98%
  • O4578

    Oltipraz

    Antioxidant; Nrf2 activator.

    ≥98%
  • T1844

    Telbivudine

    Nucleoside (thymidine) analog; DNA chain termin...

    ≥98%
  • N5210

    Nociceptin

    Endogenous neuropeptide, involved in opioid sig...

    ≥98%
  • T3197

    L-Thyroxine Sodium Pentahydrate

    Endogenous thyroid hormone T4.

    ≥97%
  • A2532

    AGI-6780

    Isocitrate dehydrogenase inhibitor.

    ≥98%
  • I6804

    Irbesartan

    PPARγ agonist, AT1 inhibitor.

    ≥98%
  • W2933

    WHI-P131

    JAK3 and EGFR inhibitor.

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only