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2-Tert-butyl-4-hydroxyanisole (2-BHA) is one component of butylated hydroxyanisole (BHA). This compound is commonly used as a food additive; it exhibits antioxidative activity. 2-BHA acts as a phase II enzyme inducer, increasing levels of glutathione and glutathione-S-transferase.
| Cas No. | 88-32-4 |
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| Purity | ≥99% single isomer |
| Formula | C11H16O2 |
| Formula Wt. | 180.25 |
| Chemical Name | 2-(1,1-Di-methylethyl)4-methoxyphenol |
| IUPAC Name | 3-tert-butyl-4-methoxyphenol |
| Synonym | 2-BHA |
| Melting Point | 69-71°C |
| Solubility | Insoluble in water. Soluble in ethanol, acetone, DMSO. |
| Appearance | White Crystal Powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
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| Info Sheet |
Hwang GH, Jeon YJ, Han HJ, et al. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J Vet Sci. 2014 Oct 8. [Epub ahead of print]. PMID: 25293491.
Nishiya H, Haga T, Nozue N, et al. Effects of 2(3)-tert-butyl-4-hydroxyanisole pretreatment on cefpiramide binding to mouse glutathione S-transferases. Pharmacology. 1989;39(4):213-23. PMID: 2608720.