Adrenorphin

Name: Adrenorphin
SKU: A1371
Availability: BackOrder

Product ID A1371

Cas No. 88377-68-8

Purity ≥95%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Adrenorphin is an endogenous opioid peptide produced from cleavage of proenkephalin A. Adrenorphin acts as an agonist at κ-opioid receptors (κORs) and μ-opioid receptors (μORs). Like other opioids, adrenorphin exhibits analgesic, antinociceptive, and gastrointestinal motility modulating activities. Adrenorphin also causes respiratory depression in animal models. In pheochromocytoma cells, adrenorphin inhibits catecholamine secretion. In animal models, it also inhibits urinary bladder muscle contractions.

Product Info

Cas No.	88377-68-8
Purity	≥95%
Formula	C₄₄H₆₉N₁₅O₉S
Formula Wt.	984.2
IUPAC Name	(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-N-[(2R)-1-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-5-(diaminomethylideneamino)pentanamide
Synonym	Metorphamide
Solubility	Soluble in water.

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	A1371 MSDS PDF
Info Sheet	A1371 Info Sheet PDF

References

Yanase T, Nawata H, Kato K,et al. Studies on adrenorphin in pheochromocytoma. J Clin Endocrinol Metab. 1987 Apr;64(4):692-7. PMID: 3818899.

Xu SF, Lu WX, Zhou KR, et al. The analgesic and respiratory depressant actions of metorphamide in mice and rabbits. Neuropeptides. 1985 Apr;6(2):121-31. PMID: 4000426.

Dray A, Davis TP. The proenkephalin A fragment metorphamide shows supraspinal and spinal opioid activity in vivo. Peptides. 1985 Mar-Apr;6(2):217-21. PMID: 3839922.

Weber E, Esch FS, Böhlen P, et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A. 1983 Dec;80(23):7362-6. PMID: 6316361.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Adrenorphin

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

L-Tetrahydropalmatine

Enocitabine

Galantamine Hydrobromide

CEP-32496

Tunicamycin

Blasticidin S Hydrochloride

S-(N-Methylthiocarbamoyl)-L-cysteine

Nitrendipine

Tamsulosin Hydrochloride

Nicergoline

Somatostatin-14

AICAR

Lumiracoxib

Sanguinarine Chloride

Dabrafenib

Regorafenib Monohydrate

Urocortin II, mouse

Fluphenazine Hydrochloride

Glimepiride

Taxol Side Chain Acid

Footer