LKT Labs

Biochemicals for Life Science Research

Adrenorphin

Adrenorphin

Product ID A1371
Cas No. 88377-68-8
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $98.00 Please Inquire
2 mg $168.00 Please Inquire
5 mg $295.00 Please Inquire
Bulk Quote

Quicklinks

Description

Adrenorphin is an endogenous opioid peptide produced from cleavage of proenkephalin A. Adrenorphin acts as an agonist at κ-opioid receptors (κORs) and μ-opioid receptors (μORs). Like other opioids, adrenorphin exhibits analgesic, antinociceptive, and gastrointestinal motility modulating activities. Adrenorphin also causes respiratory depression in animal models. In pheochromocytoma cells, adrenorphin inhibits catecholamine secretion. In animal models, it also inhibits urinary bladder muscle contractions.

Product Info

Cas No.

88377-68-8
Purity

≥95%
Formula

C44H69N15O9S
Formula Wt.

984.2
IUPAC Name

(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-N-[(2R)-1-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-5-(diaminomethylideneamino)pentanamide
Synonym

Metorphamide
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

A1371 MSDS PDF
Info Sheet

A1371 Info Sheet PDF

References

Yanase T, Nawata H, Kato K,et al. Studies on adrenorphin in pheochromocytoma. J Clin Endocrinol Metab. 1987 Apr;64(4):692-7. PMID: 3818899.

Xu SF, Lu WX, Zhou KR, et al. The analgesic and respiratory depressant actions of metorphamide in mice and rabbits. Neuropeptides. 1985 Apr;6(2):121-31. PMID: 4000426.

Dray A, Davis TP. The proenkephalin A fragment metorphamide shows supraspinal and spinal opioid activity in vivo. Peptides. 1985 Mar-Apr;6(2):217-21. PMID: 3839922.

Weber E, Esch FS, Böhlen P, et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A. 1983 Dec;80(23):7362-6. PMID: 6316361.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T3097

    Thymosin α-1 Acetate

    Endogenous peptide, involved in hormone regulat...

    ≥95%
  • O486181

    Omeprazole Related Compound B

    Impurity of omeprazole

    ≥99%
  • V344761

    Vitamin K2

    2-methyl-1,4-naphthoquinone derivative

    ≥98%
  • D3215

    Didymin

    Flavonoid glycoside found in citrus fruit.

    ≥98%
  • A5193

    Amygdalin

    Glucoside found in stone fruits and apples.

    ≥98%
  • D3221

    Difluoromethylornithine Hydrochloride Monohydrate

    Ornithine decarboxylase inhibitor.

    ≥98%
  • S1060

    Small Cardioactive Peptide A

    Peptide found in molluscs, cardiomodulator.

    ≥95%
  • P1917

    Phenylethyl 3-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥97%
  • E6245

    Eplerenone

    Mineralocorticoid antagonist.

    ≥99%
  • A5301

    Anacetrapib

    Cholesterol ester transfer protein inhibitor.

    ≥98%
  • T5720

    Tofacitinib Citrate

    JAK1/2/3 inhibitor.

    ≥99%
  • Z2268

    Z-FR-AMC

    Protease substrate.

    ≥95%
  • D604080

    DpC

    Anti-metastatic

    ≥99%
  • A1016

    S-Acetyl-L-glutathione

    Alters intracellular glutathione levels.

    ≥98%
  • V3277

    Vitamin E

    Synthetic vitamin E, antioxidant.

    ≥98%
  • D3219

    Diflubenzuron

    Benzoylurea, insect growth regulator; chitin sy...

    ≥95%
  • V3479

    Vitamin K3

    Synthetic analog of 1,4-naphthoquinone, precurs...

    ≥98%
  • Z0944

    ZCL-278

    Cdc42 inhibitor.

    ≥98%
  • Q8019

    Quetiapine Fumarate

    5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...

    ≥99%
  • S3476

    Sitagliptin Phosphate Monohydrate

    DPP4 inhibitor.

    ≥98%