Description
ADU-S100 sodium salt is a synthetic cyclic dinucleotide agonist of STING.
| Product Unit Size | Cost | Quantity | Stock |
|---|
ADU-S100 sodium salt is a synthetic cyclic dinucleotide agonist of STING.
| Cas No. | 1638750-95-4 |
|---|---|
| Purity | ≥99% |
| Formula | C20H22N10O10P2S2 • 2Na |
| Formula Wt. | 734.5 |
| IUPAC Name | Disodium;(1R,6R,8R,9R,10S,15R,17R)-8,17-bis(6-aminopurin-9-yl)-3,12-dihydroxy-3,12-bis(sulfanylidene)-2,4,7,11,13,16-hexaoxa-3λ5,12λ5-diphosphatricyclo[13.2.1.06,10]octadecane-9,18-diol |
| Synonym | ML RR-S2 CDA Sodium Salt; STING-Inducer-1; MIW815; GTPL10192; Dithio-(Rp,Rp)-[cyclic[A(2',5')pA(3',5')p]] |
| Solubility | Soluble in water (>36.7 mg/mL, >50 mM) |
| Appearance | White crystalline powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sivick KE, Desbien AL, Glickman LH, et al. Magnitude of therapeutic STING activation determines CD8+ cell-mediated anti-tumor immunity. Cell Rep. 2018 Dec 11;25(11):3074-3085. PMID: 30540940.
Insect sterilizer; mutagenic.
M4 mAChR agonist, 5-HT1A partial agonist, M1/2/...
p110α PI3K inhibitor.
EGFR (T790M) inhibitor.
Byproduct of L-arginine metabolism found in wat...
Alkaloid found in Sophora.
BRD binding agent, CDK1/2/5/9 inhibitor.
Induces activation of Nrf2; inhibits apoptosis ...
Triazole; demethylation inhibitor.
FIASMA, SERT and NET inhibitor, mAChR antagonis...
Fetal hemoglobin stimulator; ribonucleotide red...
Histone H2-derived antimicrobial peptide found ...
MEK1/2 inhibitor.
Vitamin E component
Endogenous peptide hormone, involved in growth ...
Atazanavir metabolite; HIV protease inhibitor.<...
Camptothecin derivative; topoisomerase I inhibi...
Nav1.8 Na+ channel blocker, potential Nav1.5 Na...
Cysteine-ITC conjugate, BITC derivative, antiox...
Flavonoid glycoside found in fruit, asparagus, ...