Description
ADU-S100 sodium salt is a synthetic cyclic dinucleotide agonist of STING.
Product Unit Size | Cost | Quantity | Stock |
---|
ADU-S100 sodium salt is a synthetic cyclic dinucleotide agonist of STING.
Cas No. | 1638750-95-4 |
---|---|
Purity | ≥99% |
Formula | C20H22N10O10P2S2 • 2Na |
Formula Wt. | 734.5 |
IUPAC Name | Disodium;(1R,6R,8R,9R,10S,15R,17R)-8,17-bis(6-aminopurin-9-yl)-3,12-dihydroxy-3,12-bis(sulfanylidene)-2,4,7,11,13,16-hexaoxa-3λ5,12λ5-diphosphatricyclo[13.2.1.06,10]octadecane-9,18-diol |
Synonym | ML RR-S2 CDA Sodium Salt; STING-Inducer-1; MIW815; GTPL10192; Dithio-(Rp,Rp)-[cyclic[A(2',5')pA(3',5')p]] |
Solubility | Soluble in water (>36.7 mg/mL, >50 mM) |
Appearance | White crystalline powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Sivick KE, Desbien AL, Glickman LH, et al. Magnitude of therapeutic STING activation determines CD8+ cell-mediated anti-tumor immunity. Cell Rep. 2018 Dec 11;25(11):3074-3085. PMID: 30540940.
Endogenous neuropeptide involved in hormone rel...
Endogenous peptide hormone; CCK2 agonist, indir...
STING inhibitor
Polycationic aminoglycoside; protein translatio...
Endogenous quaternary ammonium, required for fa...
Natural antibiotic found in Streptomyces parvul...
Produced by Aspergillus; type 2 methionine amin...
Azoxy compound
Endogenous heptapeptide; P2X3 and N-formylpepti...
BH3 mimetic; Bcl-2 inhibitor.
Inhibitor of ALK2, ALK3, ALK6, and AMPK.
Antimicrobial peptide, generated during fibrin ...
Inert clozapine analog, activates specialized G...
Adenosine A2A agonist.
NO donor.
Vitamin B6 derivative, antioxidant.
AurKA/B inhibitor.
Triterpene saponin found in species of Panax; P...
Found in plants in Astragalus, Allium, and Bras...
Trichothecene mycotoxin produced by Fusarium.