Description
Aflatoxin Q1 is a hydroxy metabolite of the mycotoxin aflatoxin B1. Human CYP3A4 study suggests aflatoxin Q1 is a detoxification product that is no longer mutagenic.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Aflatoxin Q1 is a hydroxy metabolite of the mycotoxin aflatoxin B1. Human CYP3A4 study suggests aflatoxin Q1 is a detoxification product that is no longer mutagenic.
| Cas No. | 52819-96-2 |
|---|---|
| Purity | ≥98% |
| Formula | C17H12O7 |
| Formula Wt. | 328.27 |
| Chemical Name | (3S,6aR,9aS)-3-hydroxy-4-methoxy-2,3-dihydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11(6aH,9aH)-dione |
| IUPAC Name | (3S,6aR,9aS)-3-Hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione |
| Synonym | AFQ1 |
| Appearance | Off white powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Yourtee DM, Bean TA, Kirk-Yourtee CL. Human aflatoxin B1 metabolism: an investigation of the importance of aflatoxin Q1 as a metabolite of hepatic post-mitochondrial fraction. Toxicol Lett. 198738(3):213-24. doi: 10.1016/0378-4274(87)90002-6, PMID: 3116726
M. Yamada , K. Hatsuta , M Niikawa, et al. Detoxification of Aflatoxin B1 Contaminated Maize Using Human CYP3A4 J. Microbiol Biotechnol 2020, 28;30(8):1207-1213. doi: 10.4014/jmb.2003.03032 PMID: 32423188
Corticosteroid; glucocorticoid agonist.
Apoptosis inducing agent.
Micronuclei formation inducer, antimitotic, oxi...
Furocoumarin; voltage-gated Na+ channel blocker...
CRF-related peptide found in amphibians.
Endogenous peptide hormone, involved in enteric...
Macrolide antibiotic; peptidyl transferase inhi...
TTK/CLK2 inhibitor.
HDAC6/10 inhibitor.
Non-depolarizing NMJ blocker; nAChR and M2/3 mA...
Triterpene saponin found in Dipsacus asper.
Synthetic peptide, stimulates gastric acid secr...
Synephrine is an endogenous alkaloid.
Synthetic cafestol derivative.
H+/K+ ATPase inhibitor.
Melatonin analog; MT1/2 agonist.
5-HT3 antagonist.
Quaternary ammonium cationic surfactant, dissoc...
Amide form of vitamin B3 required for productio...
Diterpene alkaloid found in Aconitum; voltage-g...