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Alfuzosin Hydrochloride

Alfuzosin Hydrochloride

Product ID A4523
Cas No. 81403-68-1
Purity ≥97%
Product Unit SizeCostQuantityStock
100 mg $188.70 In stock
500 mg $339.70 In stock
1 g $591.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
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  • Downloads
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Description

Alfuzosin is an α1-adrenergic receptor antagonist that is used clinically to treat benign prostatic hyperplasia (BPH); it relaxes prostatic smooth muscle and increases the urinary flow rate. Alfuzosin also delays cardiac repolarization by increasing the Na+ current. This compound prolongs action potential duration and the QT interval in vivo by increasing the probability of hNa(v)1.5 channel openings and burst duration.

Product Info

Cas No.

81403-68-1

Purity

≥97%

Formula

C19H27N5O4 • HCl

Formula Wt.

425.91

Chemical Name

(2RS)-N-[3-[(4-Amino-6, 7-dimethoxyquinazolin-2-yl)methylamino]propyl]tetrahydrofuran-2-carboxamide hydrochloride

IUPAC Name

N-[3-[(4-amino-6, 7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide; hydrochloride

Melting Point

229-231C

Appearance

White to off white powder Crystalline

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

A4523 MSDS PDF

Info Sheet

A4523 Info Sheet PDF

References

Lacerda AE, Kuryshev YA, Chen Y, et al. Alfuzosin delays cardiac repolarization by a novel mechanism. J Pharmacol Exp Ther. 2008 Feb;324(2):427-33. PMID: 17986649.

Lee M. Alfuzosin hydrochloride for the treatment of benign prostatic hyperplasia. Am J Health Syst Pharm. 2003 Jul 15;60(14):1426-39. Erratum in: Am J Health Syst Pharm. 2004 Mar 1;61(5):437. PMID: 12892027.

Dutkiewics S. Efficacy and tolerability of drugs for treatment of benign prostatic hyperplasia. Int Urol Nephrol. 2001;32(3):423-32. PMID: 11583366.

Custom Order

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