• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Allopurinol

Allopurinol

Product ID A4445
Cas No. 315-30-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $39.00 In stock
10 g $45.50 In stock
50 g $64.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Allopurinol is a purine analog that mimics hypoxanthine, inhibiting xanthine oxidase; it is clinically used to treat diseases of hyperuricemia, such as gout. Allopurinol exhibits anti-inflammatory, nephroprotective, antinociceptive, antioxidative, anti-fibrotic, and cardioprotective activities. In animal models of renal ischemia, allopurinol decreases production of inflammatory cytokines. In other animal models, allopurinol decreases oxidative stress, suppresses atrial fibrosis, and prevents atrial fibrillation. Additionally, this compound also decreases nociception in animal models of thermal and chemical pain, likely due to increasing levels of hypoxanthine and xanthine, which are metabolized downstream to form adenosine.

Product Info

Cas No.

315-30-0

Purity

≥98%

Formula

C5H4N4O

Formula Wt.

136.11

Chemical Name

1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

IUPAC Name

1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one

Synonym

Adenock, Apurol, Allozym, Apurin, Bloxanth, Embarin, Gichtex, Ketanrift, Lysuron, Urosin, Zyloric

Melting Point

>350°C

Solubility

20mg/mL in DMSO 0.5mg/mL in MeOH 0.30 mg/mL in EtOH 0.48 mg/mL in water

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A4445 MSDS PDF

Info Sheet

A4445 Info Sheet PDF

References

Prieto-Moure B, Carabén-Redaño A, Aliena-Valero A, et al. Allopurinol in renal ischemia. J Invest Surg. 2014 Oct;27(5):304-16. PMID: 24914485.

Essawy SS, Elbaz AA. Role of adenosine receptors in the anti-nociceptive effects of allopurinol in mice. Eur Rev Med Pharmacol Sci. 2013 Jul;17(14):1857-63. PMID: 23877847.

Sakabe M, Fujiki A, Sakamoto T, et al. Xanthine oxidase inhibition prevents atrial fibrillation in a canine model of atrial pacing-induced left ventricular dysfunction. J Cardiovasc Electrophysiol. 2012 Oct;23(10):1130-5. PMID: 22587612.

Pacher P, Nivorozhkin A, Szabó C. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev. 2006 Mar;58(1):87-114. PMID: 16507884.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • I4934

    Imipenem Monohydrate

    Carbapenem β-lactam; penicillin binding protei...

    ≥98%
  • C0365

    Carvedilol

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • M3368

    Mirtazapine

    Piperazine; 5-HT1 agonist, 5-HT2/3 and α2-adre...

    ≥98%
  • L5624

    Loganin

    Iridoid glucoside found in Cornus officialis; Î...

    ≥98%
  • T4800

    TM3-0089 Sodium Monohydrate

    CRTH2 inhibitor.

    ≥98%
  • P577520

    Ponatinib

    pan-Bcr-Abl tyrosine kinase inhibitor.

    ≥99%
  • Z3463

    Ziprasidone

    5-HT1A agonist, D2, 5-HT1D antagonist.

    ≥98%
  • S7061

    SRPIN340

    SRPK1 inhibitor.

    ≥98%
  • P6958

    Protopanaxatriol

    Triterpene sapogenin found in species of Panax;...

    ≥95%
  • G5874

    Gossypol

    Polyphenol found in Gossypium; calcineurin and ...

    ≥98%
  • F130280

    FHD-286

    BRG1/BRM ATPase inhibitor

    ≥98%
  • G3462

    Ginsenoside F3

    Triterpene saponin found in species of Panax.

    ≥98%
  • F465818

    Fluorouracil Impurity B

    Fluorouracil impurity

    ≥95%
  • D1722

    Defactinib

    FAK inhibitor.

    ≥98%
  • T0099

    10-Deacetylbaccatin-III

    Diterpene found in Taxus.

    ≥98%
  • P7082

    Prulifloxacin

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • A706840

    ARV-825

    Degrades of BET proteins.

    ≥99%
  • V0145

    Valinomycin

    Peptide, neutral ionophore.

    ≥98%
  • C1844

    Celastrol

    Triterpene isolated Trypterigium wilfordii; HSP...

    ≥98%
  • D5690

    Doxazosin Mesylate

    Quinazoline; α1-adrenergic antagonist.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only