Description
Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, anticoagulant, and anticancer chemotherapeutic activities. Deracoxib inhibits COX-2 and is clinically used to treat osteoarthritis in veterinary subjects. Deracoxib also decreases platelet aggregation in vivo. In mammary tumor cells, deracoxib induces apoptosis, decreases cell viability, and induces G0/G1 phase cell cycle arrest; similarly, this compound inhibits tumor growth in animal models of bladder transitional cell carcinoma.