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Alyssin

Alyssin

Product ID A4496
Cas No. 646-23-1
Purity ≥97%
Product Unit SizeCostQuantityStock
25 mg $233.60 In stock
50 mg $418.10 In stock
100 mg $741.40 In stock
500 mg $2,366.40 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Alyssin is a sulfinyl analog of sulforaphane, an isothiocyanate (ITC). Alyssin exhibits antioxidative and anticancer activity. This compound inhibits the growth of colon cancer cells in vitro and induces phase II enzymes, increasing Nrf2 activity. Alyssin also decreases enzymatic metabolism of polycyclic aromatic hydrocarbons (PAHs), decreasing carcinogenic risk and displaying potential chemopreventive benefit.

Product Info

Cas No.

646-23-1

Purity

≥97%

Formula

C7H13NOS2

Formula Wt.

191.32

Chemical Name

1-Isothiocyanato-5-(methylsulfinyl)pentane;

IUPAC Name

1-isothiocyanato-5-methylsulfinylpentane

Synonym

5-methylsulfinylpentyl isothiocyanate, 5-(Methylsulfinyl)-pentyl isothiocyanate

Solubility

Soluble in water, DMSO, ethanol, chloroform.

Appearance

Slightly yellowish liquid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A4496 MSDS PDF

Info Sheet

A4496 Info Sheet PDF

References

Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.

Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.

Skupinska K, Misiewicz-Krzeminska I, Stypulkowski R, et al. Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene. J Biochem Mol Toxicol. 2009 Jan-Feb;23(1):18-28. PMID: 19202560.

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