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Aminophylline Dihydrate

Aminophylline Dihydrate

Product ID A5135
Cas No. 5897-66-5
Purity ≥98%
Product Unit SizeCostQuantityStock
25 g $48.50 In stock
100 g $97.20 In stock
500 g $193.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Aminophylline is a non-selective adenosine receptor antagonist and phosphodiesterase (PDE) inhibitor. Aminophylline exhibits vasodilatory and anti-inflammatory activity and is occasionally clinically used to treat chronic obstructive pulmonary disorder (COPD). In animal models of allergen-induced lung inflammation, aminophylline decreases levels of IL-5, IL-8, and eosinophils.

Product Info

Cas No.

5897-66-5

Purity

≥98%

Formula

C16H24N10O4 • 2H2O

Formula Wt.

456.47

Chemical Name

3,7-Dihydro-1,3-dimetheyl-1H-purine-2,6-dione

IUPAC Name

1,3-dimethyl-7H-purine-2,6-dione;ethane-1,2-diamine;dihydrate

Synonym

Theophylline compound with ethylenediamine

Solubility

Soluble in water (1g/5mL). Insoluble in alcohol and ether.

Appearance

White to yellowish powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A5135 MSDS PDF

Info Sheet

A5135 Info Sheet PDF

References

Nickels TJ, Schwartz AD, Blevins DE, et al. Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP. Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):465-70. PMID: 16700879.

Danahay H, Broadley KJ, McCabe PJ, et al. The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways. Pulm Pharmacol Ther. 1997 Oct-Dec;10(5-6):277-85. PMID: 9778491.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
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