LKT Labs

Biochemicals for Life Science Research

Amiodarone Hydrochloride

Amiodarone Hydrochloride

Product ID A5037
Cas No. 19774-82-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $87.00 In stock
5 g $275.00 In stock
10 g $450.00 In stock
Bulk Quote

Quicklinks

Description

Amiodarone is a class III anti-arrhythmic that inhibits Na+ channels, voltage-gated Ca2+ channels, voltage-gated K+ channels, and α/β-adrenergic receptors. Amiodarone prolongs the duration of the action potential, increasing the length of the refractory period; it is clinically used to treat ventricular fibrillation and ventricular tachycardia. Amiodarone also exhibits antiviral activity, inhibiting cell entry by filovirus, guanarito virus, and hepatitis C. Additionally, this compound acts as a functional inhibitor of acid sphingomyelinase (FIASMA).

Product Info

Cas No.

19774-82-4
Purity

≥98%
Formula

C25H29I2NO3 • HCl
Formula Wt.

681.78
Chemical Name

(2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride
IUPAC Name

(2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3, 5-diiodophenyl]methanone;hydrochloride
Synonym

Amiodar, Ancaron, Cordarone, Ortacrone, Tachydaron, Trangorex  

Melting Point

156°C

Solubility

Soluble in methanol, chloroform, and methylene chloride. Slightly soluble in acetone and dioxane. Sparingly soluble in isopropanol.

Appearance

White or almost white Crystal Powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

A5037 MSDS PDF
Info Sheet

A5037 Info Sheet PDF

References

Zoerner F, Semenas E. Resuscitation with amiodarone increases survival after hemorrhage and ventricular fibrillation in pigs. J Trauma Acute Care Surg. 2014 Jun;76(6):1402-8. PMID: 24854308.

Gehring G, Rohrmann K, Atenchong N, et al. The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry. J Antimicrob Chemother. 2014 Apr 7. [Epub ahead of print]. PMID: 24710028.

Cheng YL, Lan KH, Lee WP, et al. Amiodarone inhibits the entry and assembly steps of hepatitis C virus life cycle. Clin Sci (Lond). 2013 Nov;125(9):439-48. PMID: 23659500.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • L337521

    Linagliptin

    Modifies microvascular function

    ≥98%
  • A1332

    Adipokinetic Hormone II from Locusta migratoria

    Neuropeptide found in Locusta migratoria.

    ≥98%
  • C000082

    C-82

    beta-catenin inhibitor

    ≥99%
  • A2077

    Afatinib

    EGFR inhibitor.

    ≥98%
  • G4796

    Glycerol Monolaurate

    Surfactant found in coconut oil.

    ≥98%
  • F1992

    Fexaramine

    FXR agonist.

    ≥98%
  • C022692

    Carbinoxamine Maleate

    Histamine H1-antagonist

    ≥98%
  • S8246

    Sulfadimethoxine

    Sulfonamide; folic acid synthesis inhibitor.

    ≥98%
  • H1992

    Hexaconazole

    Triazole; demethylation inhibitor.

    ≥95%
  • L5873

    Losartan Potassium

    AT1 antagonist.

    ≥98%
  • D1631

    Dehydrocorydaline

    Alkaloid compound originally found in Corydalis...

    ≥95%
  • I5414

    Indapamide

    Thiazide-like diuretic; Kv7.1 and minK K+ chann...

    ≥98%
  • B3472

    4,4′-(1,1′-Biphenyl-4,4′-diyldioxy)dianiline

    Potential VEGFR2, Met, RET, Axl, Ron, PDGFR, FG...

    ≥98%
  • T6902

    Tranilast

    Mast cell stabilizer; TRPV2 antagonist, PDGFR i...

    ≥98%
  • C224760

    CFT-7455

    Degrader of IKZF1/3

    ≥98%
  • J0378

    Jatrorrhizine

    Alkaloid compound originally found in Corydalis...

    ≥98%
  • T5060

    TMP-269

    HDAC inhibitor.

    ≥98%
  • C5662

    Copper Bis-3,5-diisopropylsalicylate

    Antioxidant.

    ≥97%
  • S8012

    [Sar9]-Substance P

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • I0417

    R-(−)-Iberin

    Sulforaphane homolog, ITC found in cruciferous ...

    ≥98%