Description
Angiotensin peptides exhibit pressor (vasoconstrictive) activity through binding of the angiotensin II type 1 (AT1) receptor, increasing blood pressure and volume.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Angiotensin peptides exhibit pressor (vasoconstrictive) activity through binding of the angiotensin II type 1 (AT1) receptor, increasing blood pressure and volume.
| Cas No. | 51833-78-4, 39386-80-6 |
|---|---|
| Purity | ≥95% |
| Formula | C41H62N12O11 |
| Formula Wt. | 899 |
| Chemical Name | L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-proline |
| IUPAC Name | (2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acid |
| Synonym | Angiotensin I (1-7), Angiotensin II (1-7), Angiotensin (1-7), 8-Des-phe-angiotensin II, TXA127, DRVYIHP |
| Solubility | Soluble in water/Acetonitrile |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Moon JY. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-45. PMID: 24627703.
Herichova I, Szantoova K. Renin-angiotensin system: upgrade of recent knowledge and perspectives. Endocr Regul. 2013 Jan;47(1):39-52. PMID: 23363256.
Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.
Microtubule polymerization inhibitor.
NDRI inhibitor
Endogenous alkaloid also found in citrus fruits...
NSAID; COX-1/2 and PDE inhibitor.
Non-selective CB receptor agonist.
5-HT1A partial agonist, 5-HT2, histamine, α1/2...
ALK4/5/7 (activin-like) inhibitor, TGF-β inhib...
NSAID; COX-1/2 inhibitor.
ALK5 (activin-like) antagonist.
Basic phenol skeleton structure found in variou...
Triazole; 14-α demethylase inhibitor, potentia...
Endogenous opioid peptide; μOR agonist.
ITC found in cruciferous vegetables; AhR antago...
Peptide, GLP-1 analog found in Heloderma; GLP-1...
Fibrate; PPARα agonist.
Cephalosporin analogue
Synthetic antioxidant that induces phase II enz...
Endogenous steroid hormone, involved in regulat...
Potent and selective inhibitor
NSAID; NMDA inverse agonist, T-type Ca2+ and Cl...