• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
AT-7519 free base

AT-7519 free base

Product ID A761001
Cas No. 844442-38-2
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $99.80 In stock
25 mg $341.30 In stock
100 mg $682.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AT-7519 is an ATP competitive CDK inhibitor showing activity against CDK1, 2, 4, 6, and 9. It causes cell cycle arrest followed by apoptosis in human tumor cells and inhibits tumor growth in human tumor xenograft models. It also induces apoptosis in multiple myeloma cells via GSK-3β activation.

Product Info

Cas No.

844442-38-2

Purity

≥98%

Formula

C16H17Cl2N5O2

Formula Wt.

382.25

Chemical Name

n-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1h-pyrazole-3-carboxamide

IUPAC Name

4-[(2,6-Dichlorobenzoyl)amino]-N-(4-piperidinyl)-1H-pyrazole-3-carboxamide

Synonym

AT7519; 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A761001 MSDS PDF

Info Sheet

A761001 Info Sheet PDF

References

Santo L., Vallet S., et al. AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition. Oncogene. 29:2325-2336 (2010). PMID: 20101221.

Squires M., Feltell R., et al. Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines. Molecular Cancer Therapeutics. 8(2):324-332 (2009). PMID: 19174555.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • L1735

    Levitide

    Antimicrobial peptide found in amphibians.

    ≥95%
  • T1030

    N-Des-2-methylpropan-2-ol Docetaxel

    N-Des-2-methylpropan-2-ol Docetaxel is an impur...

    ≥90%
  • G3460

    Ginsenoside F1

    Triterpene saponin found in species of Panax.

    ≥98%
  • C0151

    α-Calcitonin Gene Related Peptide, human

    Endogenous calcitonin-family peptide, involved ...

    ≥95%
  • C7992

    CTX-0294885

    Bisaniline pyrimidine; pan-kinase inhibitor.

    ≥98%
  • F5773

    Fosinopril Sodium

    ACE inhibitor.

    ≥98%
  • C2951

    Chlortetracycline Hydrochloride

    Tetracycline; protein translation inhibitor, MM...

    ≥85%
  • T1670

    Terazosin Hydrochloride Dihydrate

    Quinazoline; α1-adrenergic antagonist.  
    ≥98%
  • P8169

    Purpurin

    Anthraquinone pigment found in madder root; O-a...

    ≥90%
  • F5873

    Foscarnet Sodium Hydrate

    Metal ion chelator, viral DNA polymerase inhibi...

    ≥98%
  • E8419

    Everolimus

    mTORC1 inhibitor.

    ≥98%
  • H1648

    Hemorphin-7

    Endogenous opioid peptide derived from the β-c...

    ≥95%
  • B1755

    Benzimidazole

    Microtubule polymerization inhibitor, potential...

    ≥98%
  • A7578

    Astragaloside IV

    Found in Astragalus membranaceus.

    ≥98%
  • S0048

    Salicin

    Alcoholic β-glucoside found in willow bark, sa...

    ≥98%
  • G3461

    Ginsenoside F2

    Triterpene saponin found in species of Panax.

    ≥98%
  • N1755

    Neomycin Sulfate

    Polycationic aminoglycoside; protein translatio...

    ≥98%
  • A5235

    Amitriptyline Hydrochloride

    FIASMA, σ1, RyR2, TrkA/B agonist; SERT, NET in...

    ≥98%
  • R6052

    Recombinant Mycoplasma Pneumonia Antigen

    Pneumonia antigen

  • S6168

    Spirapril Hydrochloride

    ACE inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only