• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
AZD-3514

AZD-3514

Product ID A9713
Cas No. 1240299-33-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $105.00 In stock
5 mg $236.30 In stock
25 mg $892.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AZD-3514 is an anticancer chemotherapeutic that downregulates androgen receptor levels and inhibits nuclear translocation of androgen receptors. This compound exhibits efficacy in prostate cancer subjects in clinical settings. In vivo, AZD-3514 suppresses tumor growth. AZD-3514 also inhibits seminal vesicle development in juvenile animal models.

Product Info

Cas No.

1240299-33-5

Purity

≥98%

Formula

C25H32F3N7O2

Formula Wt.

519.57

Chemical Name

1-{4-[2-(4-{1-[3-(Trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-4-piperidinyl}phenoxy)ethyl]-1-piperazinyl}ethanone

IUPAC Name

1-{4-[2-(4-{1-[3-(Trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-4-piperidinyl}phenoxy)ethyl]-1-piperazinyl}ethanone

Synonym

AZD3514

Solubility

DMSO 100 mg/mL Ethanol 100 mg/mL Water Insoluble

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A9713 MSDS PDF

Info Sheet

A9713 Info Sheet PDF

References

Omlin A, Jones RJ, van der Noll R, et al. AZD3514, an oral selective androgen receptor down-regulator in patients with castration-resistant prostate cancer - results of two parallel first-in-human phase I studies. Invest New Drugs. 2015 Jun;33(3):679-90. PMID: 25920479.

Loddick SA, Ross SJ, Thomason AG, et al. AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo. Mol Cancer Ther. 2013 Sep;12(9):1715-27. PMID: 23861347.

Bradbury RH, Acton DG, Broadbent NL, et al. Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer. Bioorg Med Chem Lett. 2013 Apr 1;23(7):1945-8. PMID: 23466225.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5037

    Amiodarone Hydrochloride

    Voltage-gated Na+, Ca2+, K+ channel blocker, α...

    ≥98%
  • N1986

    Neuropeptide Y, human/rat

    Endogenous peptide neurotransmitter, involved i...

    ≥95%
  • V5886

    Voriconazole

    Triazole; 14α demethylase inhibitor.

    ≥98%
  • P4782

    PluriSIn 1

    Stearoyl-coA desaturase 1 inhibitor.

    ≥98%
  • S0929

    SCH-772984

    ERK1/2 inhibitor.

    ≥97%
  • D3374

    Disulfiram

    Aldehyde dehydrogenase, 26S proteasome, MGMT in...

    ≥98%
  • M1335

    Mdivi-1

    Quinazolinone; mitochondrial division inhibitor...

    ≥98%
  • A0402

    Abacavir Sulfate

    Nucleoside (guanosine) analog; RT, guanylyl cyc...

    ≥98%
  • I0801

    IC261

    Casein kinase 1 inhibitor.

    ≥98%
  • P0218

    Paeoniflorin

    Found in Paeonia; L-type Ca2+ channel blocker.<...

    ≥98%
  • E8401

    Evacetrapib

    Cholesterol ester transfer protein inhibitor.

    ≥98%
  • R0245

    Raltitrexed

    Folate analog; thymidylate synthase inhibitor.<...

    ≥98%
  • S0831

    S-(−)-Schisandrin B

    Found in Schisandra.

    ≥98%
  • A1331

    Adipokinetic Hormone, locust

    Neuropeptide hormone found in insects, involved...

    ≥95%
  • B8070

    2-tert-Butyl-4-Hydroxyanisole

    BHA derivative, antioxidative food and cosmetic...

    ≥99% single isomer
  • S164098

    Seco-rapamycin

    Rapamycin analog

    ≥73%
  • C1621

    CEF4

    Peptide, vSrc-induced cytokine.

    ≥95%
  • P0392

    Paxilline

    Neuroactive mycotoxin produced by Penicillum an...

    ≥98%
  • O9201

    Oxaliplatin

    Pt-based DNA cross-linker.

    ≥98%
  • A9818

    Azelastine Hydrochloride

    TRPV1 agonist, histamine H1 antagonist.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only