• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Bafilomycin B1

Bafilomycin B1

Product ID B0026
Cas No. 88899-56-3
Purity ≥97%
Product Unit SizeCostQuantityStock
0.5 mg $117.70 Please Inquire
1 mg $313.00 In stock
5 mg $1,001.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Bafilomycin B1 is a macrolide antibiotic that also exhibits antifungal activity. Bafilomycin B1 inhibits the vacuolar H+ ATPase. Additionally, bafilomycin B1 inhibits Foxo1 and increases β cell apoptosis, accelerating the onset of diabetes.

Product Info

Cas No.

88899-56-3

Purity

≥97%

Formula

C44H65NO13

Formula Wt.

815.99

Chemical Name

Hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)carbonyl)-2-methoxy-24-methyl-

IUPAC Name

[(2R,4R,5S,6R)-2-hydroxy-2-[(2S,3R,4S)-3-hydroxy-4-[(3S,4Z,6Z,9S,10S, 11R,12Z,14E)-10-hydroxy-3,15-dimethoxy-7,9,11, 13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12, 14-tetraen-2-yl]pentan-2-yl]-5-methyl-6-propan-2-yloxan-4-yl] (E)-4-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-4-oxobut-2-enoate

Synonym

Setamycin

Melting Point

89-96°C (dec)

Solubility

Soluble in methanol.

Appearance

Yellow Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B0026 MSDS PDF

Info Sheet

B0026 Info Sheet PDF

References

Schachtschabel D, Arentshorst M, Lagendijk EL, et al. Vacuolar H(+)-ATPase plays a key role in cell wall biosynthesis of Aspergillus niger. Fungal Genet Biol. 2012 Apr;49(4):284-93. PMID: 22222772.

Hettiarachchi KD, Zimmet PZ, Danial NN, et al. Transplacental exposure to the vacuolar-ATPase inhibitor bafilomycin disrupts survival signaling in beta cells and delays neonatal remodeling of the endocrine pancreas. Exp Toxicol Pathol. 2008 Aug;60(4-5):295-306. PMID: 18486461.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • L0360

    Lapatinib Ditosylate Monohydrate

    EGFR inhibitor.

    ≥99%
  • G0180

    Gastrin I, human

    Endogenous peptide hormone involved in feeding ...

    ≥98%
  • R0247

    Raltegravir

    HIV integrase inhibitor.

    ≥99%
  • SC7056

    Snake venom – Crotalus durissus terrificus

    Snake venom found in Crotalus durrisus terrific...

    ≥98%
  • D5753

    Donepezil Hydrochloride

    GSK3 and AChE inhibitor, potential σ1 agonist....

    ≥98%
  • S6019

    Speract

    Peptide, derived from egg outer envelope; K+ ch...

    ≥95%
  • M5610

    Moclobemide

    MAO-A inhibitor.

    ≥98%
  • C291342

    CHIR-99021

    GSK3 inhibitor.

    ≥98%
  • V5870

    Vortioxetine

    5-HT1A agonist, 5-HT1B partial agonist, 5-HT3A/...

    ≥99%
  • G1310

    GDC-0349

    mTOR inhibitor.

    ≥98%
  • E7433

    Etidronate Disodium

    Bisphosphonate, chelating agent.

    ≥98%
  • P333400

    PIK-75

    p110α inhibitor.

    ≥99%
  • T1002

    2-Debenzoyl Paclitaxel-2-(2-Methyl-2-Butenoate)

    Synthesis intermediate

    ≥95%
  • A600002

    AP-26113

    Pan inhibitor of ALK.

    ≥98%
  • G3553

    Ginsenoside Rb2

    Triterpene saponin found in species of Panax.

    ≥98%
  • N344784

    N-Nitroso Valsartan

    Valsartan impurity

    ≥98%
  • L8010

    D-Luciferin Potassium

    Heterocyclic light-emitting compound, natural l...

    ≥98%
  • L3454

    Lincomycin Hydrochloride Monohydrate

    Lincosamide; peptidyl transferase inhibitor, pr...

    ≥98%
  • U682040

    URB597

    FAAH inhibitor.

    ≥98%
  • C324091

    Ciclesonide

    Corticosteroid

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only