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Benzyl selenocyanate is an organoselenium compound found in selenium-enriched garlic. Benzyl selenocyanate exhibits chemopreventive activity. This compound inhibits carcinogenesis induced by DMBA, azoxymethane, or benzo[a]pyrene in various animal models. Benzyl selenocyanate may also inhibit DNA cytosine methyltransferase, PKA, and PKC.
| Cas No. | 4671-93-6 |
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| Purity | ≥98% |
| Formula | C8H7NSe |
| Formula Wt. | 196.11 |
| Chemical Name | Benzyl selenocyanate |
| IUPAC Name | benzyl selenocyanate |
| Synonym | Selenocyanic acid, benzyl ester, Selenocyanic acid, phenylmethyl ester (9CI) |
| Appearance | Clearish/white crystalline powder |
| Store Temp | 4°C |
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| Ship Temp | Ambient |
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El-Bayoumy K, Sinha R, Pinto JT, et al. Cancer chemoprevention by garlic and garlic-containing sulfur and selenium compounds. J Nutr. 2006 Mar;136(3 Suppl):864S-869S. PMID: 16484582.
Fiala ES, Staretz ME, Pandya GA, et al. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation. Carcinogenesis. 1998 Apr;19(4):597-604. PMID: 9600343.
Foiles P, Fujiki H, Suganuma M, et al. Inhibition of pkc and pka by chemopreventive organoselenium compounds. Int J Oncol. 1995 Sep;7(3):685-90. PMID: 21552892.