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BI-2536

BI-2536

Product ID B3200
Cas No. 755038-02-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $78.80 In stock
5 mg $126.00 In stock
10 mg $210.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

BI-2536 is a polo-like kinase 1 (PLK1) inhibitor that disrupts mitosis and cell division. BI-2536 exhibits anticancer activity and may induce apoptosis in cancer cells.

Product Info

Cas No.

755038-02-9

Purity

≥98%

Formula

C28H39N7O3

Formula Wt.

521.65

IUPAC Name

4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide

Synonym

BI2536

Solubility

Ethanol 100 mg/mL (191.69 mM) DMSO 21 mg/mL (40.25 mM) Water Insoluble

Appearance

Pale yellow to off-white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B3200 MSDS PDF

Info Sheet

B3200 Info Sheet PDF

References

Colnaghi R, Wheatley SP. Liaisons between survivin and Plk1 during cell division and cell death. J Biol Chem. 2010 Jul 16;285(29):22592-604. PMID: 20427271.

Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nature Reviews Cancer. 2009 Jan;9:28-39.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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