• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
C-Type Natriuretic Peptide (1-22), human

C-Type Natriuretic Peptide (1-22), human

Product ID C7997
Cas No. 127869-51-6
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $147.00 In stock
1 mg $262.50 In stock
2.5 mg $472.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

C-type natriuretic peptide (CNP) is a natriuretic peptide (NP) that binds NP-B receptors. This peptide exhibits cardioprotective and anti-inflammatory activities. In animal models, CNP increases conduction velocity in the sinoatrial node and decreases infarct size in models of ischemia/reperfusion. In vitro, CNP decreases basal ATP-sensitive K+ channel openings and currents. Animal models of mutant CNP display arthritis, cartilage damage, and growth delay, highlighting roles for CNP in the regulation of skeletal growth and inflammation. CNP binding NP receptors increases cGMP levels and opens cystic fibrosis transmembrane receptor (CTFR) Cl- channels in a PDE3/cAMP/PKA-dependent manner.

Product Info

Cas No.

127869-51-6

Purity

≥95%

Formula

C93H157N27O28S3

Formula Wt.

2197.64

Synonym

CNP

Solubility

Soluble in water (1 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C7997 MSDS PDF

Info Sheet

C7997 Info Sheet PDF

References

Burley DS, Cox CD, Zhang J, et al. Natriuretic peptides modulate ATP-sensitive K(+) channels in rat ventricular cardiomyocytes. Basic Res Cardiol. 2014 Mar;109(2):402. PMID: 24477916.

Azer J, Hua R, Krishnaswamy PS, et al. Effects of natriuretic peptides on electrical conduction in the sinoatrial node and atrial myocardium of the heart. J Physiol. 2014 Mar 1;592(Pt 5):1025-45. PMID: 24344164.

De Jonge HR, Tilly BC, Hogema BM, et al. cGMP inhibition of type 3 phosphodiesterase is the major mechanism by which C-type natriuretic peptide activates CFTR in the shark rectal gland. Am J Physiol Cell Physiol. 2014 Feb;306(4):C343-53. PMID: 24259420.

Bükülmez H, Khan F, Bartels CF, et al. Protective effects of C-type natriuretic peptide on linear growth and articular cartilage integrity in a mouse model of inflammatory arthritis. Arthritis Rheumatol. 2014 Jan;66(1):78-89. PMID: 24449577.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • Q8134

    Quinapril Hydrochloride

    ACE inhibitor.

    ≥98%
  • M1680

    5-Methoxyindole

    Core structure of melatonin; potential PPARγ a...

    ≥98%
  • S0930

    Schisantherin A

    Dibenzocyclooctadiene found in Schisandra.

    ≥98%
  • C0377

    Catharanthine Sulfate

    Alkaloid found in Catharanthus, precursor in sy...

    ≥98%
  • T3134

    Thiostrepton

    Thiazole; proteasome inhibitor, protein translo...

    ≥97%, HPLC
  • A4854

    β-Amyloid Peptide (1-42), rat

    Endogenous APP peptide cleavage product, primar...

    ≥95%
  • U451349

    Ulixertinib

    May induce apoptosis in lymphoma cell lines.

    ≥98%
  • I7478

    Istradefylline

    Adenosine A2A antagonist.

    ≥99%
  • V3212

    Vidarabine

    Nucleoside (adenosine) analog; viral DNA polyme...

    ≥98%
  • S164098

    Seco-rapamycin

    Rapamycin analog

    ≥73%
  • C4000

    CK-636

    Arp2/3 inhibitor.

    ≥98%
  • C0344

    Calphostin C

    Found in Cladosporium; PKC inhibitor.

    ≥95%
  • D0261

    Dapivirine

    RT inhibitor.

    ≥98%
  • M184776

    5-(Methylsulfonyl)pentyl Nitrile

    Synthetic nitrile compound

    ≥98%
  • A1370

    Adrenomedullin (22-52), human

    Endogenous peptide hormone, involved in cell gr...

    ≥95%
  • G1200

    GDC-0068

    Akt inhibitor.

    ≥98%
  • M2400

    MG-132

    Proteasome inhibitor.

    ≥98%
  • N3228

    Nifedipine

    Dihydropyridine; L-type Ca2+ channel blocker.

    ≥98%
  • P1845

    Pelitinib

    EGFR inhibitor.

    ≥98%
  • K9200

    KX1-004

    Indole; Src inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only