Description
C170 is a potent and covalent inhibitor of STING.
C170
Product ID C000170
Cas No. 346691-38-1
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 346691-38-1 |
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| Purity | ≥98% |
| Formula | C15H16N2O4 |
| Formula Wt. | 288.30 |
| Chemical Name | N-(4-butylphenyl)-5-nitrofuran-2-carboxamide |
| IUPAC Name | N-(4-butylphenyl)-5-nitrofuran-2-carboxamide |
| Synonym | STING-IN-2; STING Inhibitor C-170 |
| Solubility | Soluble in DMSO. |
| Appearance | Yellow powder |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| Info Sheet |
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References
Liu J, Yuan L, Ruan Y, et al. Novel CRBN-recruiting proteolysis-targeting chimeras as degraders of stimulator of interferon genes with in vivo anti-inflammatory efficacy. J Med Chem. 2022 May 12;65(9):6593-6611. PMID: 35452223
Haag S, Gulen M, Reymond L, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273. PMID: 29973723