LKT Labs

Biochemicals for Life Science Research

C170

C170

Product ID C000170
Cas No. 346691-38-1
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $49.70 In stock
25 mg $137.90 In stock
100 mg $413.50 In stock
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Description

C170 is a potent and covalent inhibitor of STING.

Product Info

Cas No.

346691-38-1
Purity

≥98%
Formula

C15H16N2O4
Formula Wt.

288.30
Chemical Name

N-(4-butylphenyl)-5-nitrofuran-2-carboxamide
IUPAC Name

N-(4-butylphenyl)-5-nitrofuran-2-carboxamide
Synonym

STING-IN-2; STING Inhibitor C-170
Solubility

Soluble in DMSO.
Appearance

Yellow powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

Info Sheet

C000170 Info Sheet PDF

References

Liu J, Yuan L, Ruan Y, et al. Novel CRBN-recruiting proteolysis-targeting chimeras as degraders of stimulator of interferon genes with in vivo anti-inflammatory efficacy. J Med Chem. 2022 May 12;65(9):6593-6611. PMID: 35452223

Haag S, Gulen M, Reymond L, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273. PMID: 29973723

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