Description
Penciclovir is a guanosine nucleoside analog that prevents viral replication by inducing lethal mutations and inhibits DNA polymerase. Penciclovir exhibits antiviral activity and is clinically used to treat herpes virus infections.
Product Unit Size | Cost | Quantity | Stock |
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Penciclovir is a guanosine nucleoside analog that prevents viral replication by inducing lethal mutations and inhibits DNA polymerase. Penciclovir exhibits antiviral activity and is clinically used to treat herpes virus infections.
Cas No. | 39809-25-1 |
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Purity | ≥98% |
Formula | C10H15N5O3 |
Formula Wt. | 253.26 |
Chemical Name | 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxy- methylbutyl]-6H-purin-6-one |
IUPAC Name | 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one |
Synonym | Denavir, Vectavir |
Melting Point | 275-277°C |
Solubility | Soluble in water, DMSO. |
Appearance | White to off-white crystal powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Deval J. Antimicrobial strategies: inhibition of viral polymerases by 3'-hydroxyl nucleosides. Drugs. 2009;69(2):151-66. PMID: 19228073.
Villarreal EC. Current and potential therapies for the treatment of herpes-virus infections. Prog Drug Res. 2003;60:263-307. PMID: 12790345.
Balzarini J, Bohman C, Walker RT, et al. Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells. Mol Pharmacol. 1994 Jun;45(6):1253-8. PMID: 8022417.
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